Recognizes both Abl and BCR-Abl when phosphorylated on tyrosine residue corresponding to Tyr412 in Abl.
Immunogen
KLH-conjugated peptide corresponding to amino acid region encompassing human c-Abl Tyr412.
Application
Research Category Signaling
Research Sub Category Cytoskeletal Signaling
General Post-translation Modification
This Anti-phospho-Abl (Tyr412) Antibody is validated for use in ELISA, WB for the detection of phospho-Abl (Tyr412).
Quality
Routinely evaluated by immunoblot.
Target description
145 kDa
Physical form
ImmunoAffinity Purified
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Certificates of Analysis (COA)
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The Journal of biological chemistry, 289(31), 21463-21472 (2014-06-14)
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This study sought to identify β-catenin targets that regulate desmoid oncogenesis and determine whether external signaling pathways, particularly those inhibited by sorafenib (e.g., PDGFRβ), affect these targets to alter natural history or treatment response in patients. In vitro experiments utilized
More than one-half of the interneurons in a mouse olfactory bulb (OB) develop during the first week after birth and predominantly connect to excitatory tufted cells near the superficial granule cell layer (sGCL), unlike late-born interneurons. However, the molecular mechanisms
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