561037
3,4-Difluorophenylmagnesium bromide solution
0.5 M in THF
About This Item
reaction suitability
reaction type: Grignard Reaction
Quality Level
concentration
0.5 M in THF
bp
65 °C
density
0.965 g/mL at 25 °C
storage temp.
2-8°C
SMILES string
Fc1ccc([Mg]Br)cc1F
InChI
1S/C6H3F2.BrH.Mg/c7-5-3-1-2-4-6(5)8;;/h1,3-4H;1H;/q;;+1/p-1
InChI key
WZHAVYGMKGPNFN-UHFFFAOYSA-M
Related Categories
Application
- To prepare 3,4-difluorophenylboronic acid, a key building block employed in the synthesis of norepinephrine transporter selective molecules.
- In the synthesis of trimethoxybenzophenone derived tubulin polymerization inhibitors.
- In one of the key synthetic steps for the preparation of diarylketoxime derivatives as potent MCH-1R antagonists.
- In the synthesis of biologically important hydroxybupropion analogs useful in smoking cessation.
Legal Information
Rieke is a registered trademark of Rieke Metals, Inc.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
Target Organs
Respiratory system
Supplementary Hazards
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point(F)
1.0 °F - closed cup
Flash Point(C)
-17.2 °C - closed cup
Certificates of Analysis (COA)
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