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Sigma-Aldrich

Poly(ethyleneimine) solution

average Mw 1800, 50 wt. % in H2O

Synonym(s):

Ethyleneimine polymer solution, PEI

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About This Item

CAS Number:
9002-98-6
MDL number:
MFCD00084427
UNSPSC Code:
12162002
PubChem Substance ID:
24865590
NACRES:
NA.23

form

liquid

mol wt

average Mw 1800

concentration

50 wt. % in H2O

refractive index

n20/D 1.453

density

1.08 g/mL at 25 °C

InChI

1S/C2H8N2.C2H5N/c3-1-2-4;1-2-3-1/h1-4H2;3H,1-2H2

InChI key

SFLOAOINZSFFAE-UHFFFAOYSA-N

General description

Poly(ethyleneimine) (PEI) is a positivelycharged polymeric amine with a linear or branched structure. It has chelating properties with a variety of metal ions. It is highlysoluble in water and behaves as an effective base in aqueous solutions. Due toits superior physicochemical properties, it is widely used in the field ofbiomedicine, water purification, bioimaging, gene delivery, and self-healingmaterials.

Application

Poly(ethyleneimine) solution can be used for surface modification of cation exchange resins. The modified resins exhibited improved selectivity towards transition elements. Due to repulsion effects within the cationic layer, the selectivity for alkaline ions decreases. As a result, this resin can be applied to purify industrial waste by column sorption.

It can be used as a precursor to prepare polyelectrolyte multilayers for the promotion of cell adhesion and growth on implant surfaces.

PEI can act as a reactive template and stabilizing agent in the preparation of metal nanoparticles in aqueous media. The amino groups in the PEI can coordinate with metal ions dissolved in water and reduce their aggregation capability. This results in the formation of smaller nanoparticles.

Features and Benefits

  • It has repetitive structural units and aflexible polymer chain.
  • Due to the accessibility of a huge number ofamino groups on PEI, it can be modified or functionalized for specific featuressuch as sensitivity, specificity, and biocompatibility.
  • Highwater solubility.

Physical form

Branched polymer

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H317,H411

Hazard Classifications

Aquatic Chronic 2 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Certificates of Analysis (COA)

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Functionalized PEI and Its Role in Gene Therapy

Gene therapy has become one of the most discussed techniques in biomedical research in recent years.

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