The Robo4 cytoplasmic domain is dispensable for vascular permeability and neovascularization.

The Robo4 cytoplasmic domain is dispensable for vascular permeability and neovascularization.

Nature communications (2016-11-25)

Feng Zhang, Claudia Prahst, Thomas Mathivet, Laurence Pibouin-Fragner, Jiasheng Zhang, Gael Genet, Raymond Tong, Alexandre Dubrac, Anne Eichmann

PMID27882935

RÉSUMÉ

Vascular permeability and neovascularization are implicated in many diseases including retinopathies and diabetic wound healing. Robo4 is an endothelial-specific transmembrane receptor that stabilizes the vasculature, as shown in Robo4

MATÉRIAUX

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Marque

Description du produit

F8630

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Fibrinogène from bovine plasma, Type I-S, 65-85% protein (≥75% of protein is clottable)

H3149

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MISSION^® esiRNA, targeting human ROBO1

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MISSION^® esiRNA, targeting human ROBO4

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