Lactone-free ginkgolides via regioselective DIBAL-H reduction.

Lactone-free ginkgolides via regioselective DIBAL-H reduction.

Organic & biomolecular chemistry (2005-09-21)

Hideki Ishii, Sergei V Dzyuba, Koji Nakanishi

RÉSUMÉ

The lactone rings of ginkgolide A are converted into corresponding tetrahydrofuran moieties via DIBAL-H reduction followed by deoxygenation of the formed lactols with Et3SiH-BF3.Et2O to produce a series of lactone-free ginkgolides.

MATÉRIAUX

Référence du produit

Marque

Description du produit

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