1604009

Rifampine

United States Pharmacopeia (USP) Reference Standard

• Synonyme(s) : Rifampicine, 3-(4-méthylpipérazinyliminométhyl)rifamycine SV, Rifampine, Rifamycine AMP
• Formule empirique (notation de Hill) : C₄₃H₅₈N₄O₁₂
• Numéro CAS: 13292-46-1
• Poids moléculaire : 822.94
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329751045
• MDL number: MFCD00151389
• Beilstein/REAXYS Number: 5723476

Propriétés

• grade: pharmaceutical primary standard
• agency: USP
• API family: rifampin
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(\C=N\N5CCN(C)CC5)c(O)c4c3C2=O
• InChI: 1S/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,44-20+/t21-,23+,24+,25+,29-,34-,35+,39+,43-/m0/s1
• InChI key: JQXXHWHPUNPDRT-WLSIYKJHSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Rifampin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Rifampin Capsules
• Rifampin Compounded Oral Suspension
• Rifampin and Isoniazid Capsules
• Rifampin, Isoniazid, and Pyrazinamide Tablets
• Rifampin, Isoniazid, Pyrazinamide, and Ethambutol Hydrochloride Tablets

Biochem/physiol Actions

Inhibe l'assemblage de l'ADN et de la protéine en particules virales matures.

Mode d'action : inhibe l'initiation de la synthèse de l'ARN en se liant à la sous-unité β de l'ARN polymérase.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Informations sur la sécurité

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable