Accéder au contenu
Merck
Toutes les photos(1)

Key Documents

View All Documentation

1478301

USP

Olanzapine

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

2-Methyl-4-(4-methyl-1-piperazinyl)- 10H-thieno[2,3-b][1,5]benzodiazepine

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(1)

About This Item

Formule empirique (notation de Hill):
C17H20N4S
Numéro CAS:
132539-06-1
Poids moléculaire :
312.43
Numéro Beilstein :
7655141
Numéro MDL:
MFCD00866702
Code UNSPSC :
41116107
ID de substance PubChem :
329750606
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

olanzapine

Fabricant/nom de marque

USP

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

CN1CCN(CC1)C2=Nc3ccccc3Nc4sc(C)cc24

InChI

1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3

Clé InChI

KVWDHTXUZHCGIO-UHFFFAOYSA-N

Informations sur le gène

human ... DRD2(1813) , DRD3(1814) , DRD4(1815) , HTR2A(3356) , HTR2C(3358)

Vous recherchez des produits similaires ? Visite Guide de comparaison des produits

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Olanzapine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Olanzapine and Fluoxetine Capsules
  • Olanzapine Orally Disintegrating Tablets
  • Olanzapine Tablets

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

1478312

Olanzapine Related Compound A, United States Pharmacopeia (USP) Reference Standard

1478323

Olanzapine Related Compound B, United States Pharmacopeia (USP) Reference Standard

Y0001370

Olanzapine, European Pharmacopoeia (EP) Reference Standard

Y0001380

Olanzapine for system suitability, European Pharmacopoeia (EP) Reference Standard

Y0001392

Olanzapine impurity A, European Pharmacopoeia (EP) Reference Standard

1478334

Composé C apparenté à l'olanzapine, United States Pharmacopeia (USP) Reference Standard

BP1060

Olanzapine, British Pharmacopoeia (BP) Reference Standard

Y0002177

Olanzapine embonate for peak identification, CRS, European Pharmacopoeia (EP) Reference Standard

PHR2537

Olanzapine Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2536

Olanzapine Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2538

N-Oxyde d'olanzapine, Pharmaceutical Secondary Standard; Certified Reference Material

Pictogrammes

Skull and crossbones
GHS06

Mention d'avertissement

Danger

Mentions de danger

H301,H315,H317,H336

Classification des risques

Acute Tox. 3 Oral - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Organes cibles

Central nervous system

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Les clients ont également consulté

Slide 1 of 4

1 of 4

Olanzapine-d8 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

Supelco

O-035

Olanzapine-d8

USP

USP

1478312

Olanzapine Related Compound A

USP

USP

1478334

Composé C apparenté à l'olanzapine

Risperidone ≥98% (HPLC), powder

Sigma-Aldrich

R3030

Risperidone

Rajendra P Shukla et al.
Journal of neural transmission (Vienna, Austria : 1996), 127(2), 291-299 (2020-01-08)
Olanzapine is a thienobenzodiazepine compound. It is one of the newer types of antipsychotic drugs used in the treatment of schizophrenia and other psychotic disorders. Several methods have been reported for analyzing olanzapine in its pure form or combined with
Mauricio Tohen et al.
Archives of general psychiatry, 60(11), 1079-1088 (2003-11-12)
Despite the longer duration of the depressive phase in bipolar disorder and the frequent clinical use of antidepressants combined with antipsychotics or mood stabilizers, relatively few controlled studies have examined treatment strategies for bipolar depression. To examine the use of
Delia Bishara et al.
Journal of clinical psychopharmacology, 33(3), 329-335 (2013-04-24)
To conduct a systematic review examining the relationships between olanzapine dose, clinical outcome, dopamine occupancy, and plasma concentration; and to evaluate the potential for therapeutic drug monitoring. A search using Embase, Medline, and Pubmed was conducted; and the literature was
Christopher M Hocking et al.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 22(4), 1143-1151 (2014-02-14)
Newer drugs incorporated in prophylactic regimens for chemotherapy-induced nausea and vomiting (CINV) have resulted in significantly reduced rates of this feared complication of cytotoxic chemotherapy. However, both delayed chemotherapy-induced nausea and breakthrough CINV remain difficult areas of management and require
Elizabeth Brunner et al.
BMC pharmacology & toxicology, 14, 38-38 (2013-08-02)
Olanzapine use has been reported during pregnancy and breastfeeding, but there are no controlled clinical trials assessing the safety of olanzapine exposure to infants and fetuses. The purpose of this report was to review and analyze prospective post-marketing cases of
Afficher tous les articles scientifiques apparentés

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique