PHL83418

Zerumbone

phyproof^® Reference Substance

• Synonyme(s) : (2E,6E,10E)-2,6,9,9-tetramethylcycloundeca-2,6,10-trien-1-one, Zerumbone (6CI,7CI)
• Formule empirique (notation de Hill) : C₁₅H₂₂O
• Numéro CAS: 471-05-6
• Poids moléculaire : 218.33
• Numéro MDL: MFCD03700769
• Code UNSPSC : 41116107
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: primary reference standard
• Gamme de produits: phyproof^® Reference Substance
• Essai: ≥90.0% (GC)
• Fabricant/nom de marque: PhytoLab
• Application(s): food and beverages
• Format: neat
• Température de stockage: 2-8°C
• Chaîne SMILES: C\C1=C/CC(C)(C)\C=C\C(=O)\C(C)=C\CC1
• InChI: 1S/C15H22O/c1-12-6-5-7-13(2)14(16)9-11-15(3,4)10-8-12/h7-9,11H,5-6,10H2,1-4H3/b11-9+,12-8+,13-7+
• Clé InChI: GIHNTRQPEMKFKO-SKTNYSRSSA-N

Description

Description générale

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Actions biochimiques/physiologiques

TRAIL-induced apoptosis potentiator; DR4 and DR5 inducer

Zerumbone is a TRAIL-induced apoptosis potentiator. It potentiates TRAIL-induced apoptosis through the up-regulation of DR4 and DR5 expression and the down-regulation of cFLIP. Zerumbone has very little or no cytotoxic effect on the normal human endothelial cells and dermal fibroblasts. Zerumbone is a sesquiterpene isolated from in Zingiber zerumbet Smith (wild ginger).

Autres remarques

This compound is commonly found in plants of the genus: curcuma zingiber

Informations légales

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Informations sur la sécurité

• Pictogrammes: GHS07,GHS09
• Mention d'avertissement: Warning
• Mentions de danger: H317,H400
• Conseils de prudence: P273 - P280 - P302 + P352
• Classification des risques: Aquatic Acute 1 - Skin Sens. 1
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable