569232-U

Discovery^® C18 (5 µm) HPLC Columns

L × I.D. 12.5 cm × 4.6 mm, HPLC Column

• Synonyme(s) : Discovery RP18 HPLC Column
• Code UNSPSC : 41115700
• eCl@ss : 32110501
• Nomenclature NACRES : SB.52

Propriétés

• product name: Colonne HPLC Discovery^® C18, 5 μm particle size, L × I.D. 12.5 cm × 4.6 mm
• Matériaux: stainless steel column
• Agence: suitable for USP L1
• Gamme de produits: Discovery^®
• Caractéristiques: endcapped
• Fabricant/nom de marque: Discovery^®
• Conditionnement: 1 ea of
• Ampleur du marquage: 12% Carbon loading
• Paramètres: ≤70 °C temp. range; 400 bar pressure (5801 psi)
• Technique(s): HPLC: suitable; LC/MS: suitable
• L × D.I.: 12.5 cm × 4.6 mm
• Superficie: 300 m²/g
• Couverture de surface: 3 μmol/m²
• Impuretés: <10 ppm metals
• Matrice: silica gel, high purity, spherical particle platform; fully porous particle
• Groupe de la matrice active: C18 (octadecyl) phase
• Taille des particules: 5 μm
• Dimension de pores: 180 Å
• operating pH range: 2-8
• Application(s): food and beverages
• Technique de séparation: reversed phase

Description

Description générale

Utilisez les colonnes Discovery® C18 pour toutes les méthodes qui demandent une colonne C18. La forme exceptionnelle des pics, la reproductibilité et la stabilité en font la colonne de choix pour toutes les méthodes C18, des applications de routines à celles les plus exigeantes.

Application

• Rat Pharmacokinetics and In Vitro Metabolite Identification of KM-819, a Parkinson′s Disease Candidate, Using LC-MS/MS and LC-HRMS.: This study underscores the utility of theDiscovery^® C18 HPLC Column in pharmacokinetic profiling and metabolite identification of a novel therapeutic agent, demonstrating its critical role in the development of Parkinson′s disease treatments (Choi et al., 2024).


• Determination of 2,4-dimethylhydroxybenzene by chromatographic methods in forensic toxicological research of biological material.: Highlights the application of the Discovery^® C18 HPLC Column in forensic toxicology, enhancing the detection and quantification of toxic substances within biological samples, vital for legal and medical investigations (Chernova et al., 2024).


• High-throughput microfluidic chip with silica gel-C18 channels for cyclotide separation.: Illustrates the integration of the Discovery^® C18 HPLC Column in a microfluidic setting for efficient and high-throughput separation of cyclotides, offering advancements in peptide and protein analysis (Ebrahimi et al., 2023).


• Priestia megaterium Metabolism: Isolation, Identification of Naringenin Analogues and Genes Elevated Associated with Nanoparticle Intervention.: This research utilizes the Discovery^® C18 HPLC Column for the advanced study of microbial metabolism under nanoparticle intervention, pushing the boundaries of biotechnological and pharmaceutical research (Al-Theyab et al., 2023).


• A practical strategy enabling more reliable identification of ginsenosides from Panax quinquefolius flower by dimension-enhanced liquid chromatography/mass spectrometry and quantitative structure-retention relationship-based retention behavior prediction.: Demonstrates the versatility of the Discovery^® C18 HPLC Column in complex botanical analyses, particularly in enhancing the reliability of ginsenoside identification, crucial for the development of herbal medicinal products (Sun et al., 2023).

Caractéristiques et avantages

• Reproductibilité excellente
• Forme exceptionnelle des pics des analytes basiques et acides
• Séparations LC-MS stables à faible diffusion
• Séparation des peptides et petites protéines
• Hydrophobicité moindre que celle de nombreuses colonnes comparables, produisant une analyse plus rapide

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Informations légales

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany