SRP4248

MIP-1beta from mouse

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

• Synonyme(s) : CCL4, MIP-1- β, Macrophage inflammatory protein 1-β, Small inducible cytokine A4, T-cell activation protein 2
• Numéro MDL: MFCD00213006
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.32

Propriétés

• Source biologique: mouse
• Produit recombinant: expressed in E. coli
• Essai: ≥98% (HPLC); ≥98% (SDS-PAGE)
• Forme: lyophilized
• Poids mol.: ~7.8 kDa
• Conditionnement: pkg of 10 μg
• Impuretés: endotoxin, tested
• Numéro d'accès NCBI: P14097
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Informations sur le gène: mouse ... Ccl4(20303)

Description

Description générale

Mouse macrophage inflammatory protein-1β (MIP-1β) is a 7.8 kDa protein containing 69 amino acid residues. It plays an important role in the inflammatory response of blood monocytes and tissue macrophages.
MIP-1β is mainly generated by monocytes and lymphocytes. It is a member of CC family of chemokine intercrine cytokine. MIP-1β shares 70% similarity with MIP-1α. It is localized to a number of tissues such as smooth muscles, monocytes, neutrophils, mast cells, fibroblast B and T lymphocytes.[1]

Actions biochimiques/physiologiques

Macrophage inflammatory protein-1 β (MIP-1β) promotes myelopoietic cellular growth and induces leukocyte chemoattraction. MIP-1β is an effective HIV infection suppressor.[1]

Forme physique

Lyophilized without any additives.

Reconstitution

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers.