Human Bromodomain testis-specific protein, also known as BRDT, BRD6, and CT9 (GenBank Accession No. NM_207189) amino-acids 257 – 382 with N-terminal HIS-tag, MW = 15.8 kDa, expressed in an E. coli expression system.
Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 1
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Not applicable
Point d'éclair (°C)
Not applicable
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Mice homozygous for a mutation (Brdt(∆BD1/∆BD1)) lacking the first bromodomain of Brdt, a testis-specific member of the BET family of double-bromodomain containing proteins, are sterile and exhibit profound defects in chromatin remodeling during spermiogenesis. We have now observed that a
Development (Cambridge, England), 134(19), 3507-3515 (2007-08-31)
Brdt is a testis-specific member of the distinctive BET sub-family of bromodomain motif-containing proteins, a motif that binds acetylated lysines and is implicated in chromatin remodeling. Its expression is restricted to the germ line, specifically to pachytene and diplotene spermatocytes
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