Accéder au contenu
Merck
Toutes les photos(1)

Principaux documents

SML1376

Sigma-Aldrich

BTC

≥95% (HPLC)

Synonyme(s) :

2-(4-Hydroxyphenyl)-1-benzothiophene-6-ol, 2-(4-Hydroxyphenyl)benzo[b]thiophene-6-ol

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(1)

About This Item

Formule empirique (notation de Hill) :
C14H10O2S
Numéro CAS:
63676-22-2
Poids moléculaire :
242.29
Code UNSPSC :
51111800
Nomenclature NACRES :
NA.77

Essai

≥95% (HPLC)

Forme

powder

Conditions de stockage

protect from light

Couleur

white to light brown

Solubilité

DMSO: 20 mg/mL, clear

Température de stockage

−20°C

InChI

1S/C14H10O2S/c15-11-4-1-9(2-5-11)13-7-10-3-6-12(16)8-14(10)17-13/h1-8,15-16H

Clé InChI

MDGWZLQPNOETLH-UHFFFAOYSA-N

Actions biochimiques/physiologiques

BTC is a selective estrogen receptor (ER) modulator (SERM) that acts as a selective estrogen mimic (SEM).
BTC is a selective estrogen receptor (ER) modulator (SERM) that acts as a selective estrogen mimic (SEM). BTC has been found to be both estrogenic and antiproliferative in ER-positive endocrine-resistant breast cancer cell lines that overexpress protein kinase C alpha (PKCα), which is often associated with tamoxifen resistance. BTC caused regression of endocrine-resistant breast cancer xenografts, and did not support the growth of hormone-dependent xenografts in vivo or cause an increase in uterine weight. As in the case with raloxifene and estradiol, BTC tumor regression was accompanied by the exit of ERα from the nucleus, suggesting extranuclear ERα may be involved in the mehanism of action.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302

Conseils de prudence

P301 + P312 + P330

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number
046M4706V

Vous ne trouvez pas la bonne version ?

Si vous avez besoin d'une version particulière, vous pouvez rechercher un certificat spécifique par le numéro de lot.

Rechercher un(e) COA

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Fuping Li et al.
Small (Weinheim an der Bergstrasse, Germany), 16(14), e1906276-e1906276 (2020-03-05)
Direct conversion of syngas to dimethyl ether (DME) through the intermediate of methanol allows more efficient DME production in a simpler reactor design relative to the conventional indirect route. Although Cu/ZnO-based multicomponent catalysts are highly active for methanol synthesis in
Wenjun Zhou et al.
Journal of hazardous materials, 391, 121642-121642 (2020-02-12)
To enhance the photocatalytic activity of TiO2, a new preparation method has been proposed to synthesize the catalysts by introducing Cu-MOF as a precursor and performing a blackening process via a mixture with NaBH4 for TiO2 nanoparticles (CuO-TiO2(mb)). The results
Xinyang Zhang et al.
The Analyst, 145(14), 5011-5018 (2020-06-11)
3D magnetic porous carbon (MPCK) was prepared using the metal-organic framework (MOF) MIL-100(Fe) as the carbon precursor by carbonisation and KOH activation strategies. Carbonisation and activation ensured that MPCK possessed excellent structural and thermal stability, strong magnetic responsiveness and high
Rui Pei et al.
Journal of hazardous materials, 384, 121418-121418 (2019-12-11)
Three-dimensional (3D) printing technique has received exceptional global attention as it can create a myriad of high-resolution architectures from digital models. In the present study, 3D-printed metal-organic frameworks (MOFs) were shaped into several geometries via direct ink writing, which overcomes
Jibin An et al.
Environmental research, 191, 110067-110067 (2020-08-21)
Metal-organic frameworks (MOFs) are emerging class of porous materials that attracted tremendous attention as eco-friendly photocatalysts. However, poor charge separation in most MOFs largely thwarts their photocatalytic performance. In this work, Materials of Institut Lavoisier-100(Fe) (MIL-100 (Fe)) based on iron
Afficher tous les articles scientifiques apparentés

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique