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COO/COA

SCP0259

Vasoactive Intestinal Constrictor / β Endothelin mouse

Name: Vasoactive Intestinal Constrictor / β Endothelin mouse
Brand: SIGMA

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About This Item

Formule empirique (notation de Hill):

C₁₁₆H₁₆₁N₂₇O₃₂S₄

Poids moléculaire :

2573.94

Code UNSPSC :

12352200

Nomenclature NACRES :

NA.32

Pureté

≥95% (HPLC)

Forme

lyophilized

Composition

Peptide Content, ≥75%

Conditions de stockage

protect from light

Température de stockage

−20°C

Amino Acid Sequence

Cys-Ser-Cys-Asn-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp

Application

Endothelin-2 (Vasoactive Intestinal Constrictor), mouse, a vaso-constricting peptide, is used in studies of the maintenance, protection and hyper-pigmentation of the epidermis.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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High doses of ultraviolet-C irradiation increases vasoactive intestinal contractor/endothelin-2 expression in keratinocytes of the newborn mouse epidermis.

Javier Adur et al.

Peptides, 28(5), 1083-1094 (2007-04-24)

We examined the expression profiles of vasoactive intestinal contractor/endothelin-2 (VIC/ET-2) at both gene and peptide level in skin irradiated with different ultraviolet wavelengths. We found that VIC/ET-2 gene expression is sensitive only to ultraviolet-C (UVC) irradiation and has an immediate

Endothelin-2/vasoactive intestinal contractor via ROCK regulates transglutaminase 1 on differentiation of mouse keratinocytes.

Eiichi Kotake-Nara et al.

Biochemical and biophysical research communications, 357(1), 168-173 (2007-04-10)

We previously found that endothelin-2/vasoactive intestinal contractor (ET-2/VIC) greatly increased in mouse epidermis after birth. In the present study, we evaluated whether ET-2/VIC expression was associated with the calcium-induced differentiation of cultured mouse keratinocytes. The differentiation induction was revealed by

Endothelin-2/vasoactive intestinal contractor: regulation of expression via reactive oxygen species induced by CoCl2, and Biological activities including neurite outgrowth in PC12 cells.

Eiichi Kotake-Nara et al.

TheScientificWorldJournal, 6, 176-186 (2006-02-24)

This paper reviews the local hormone endothelin-2 (ET-2), or vasoactive intestinal contractor (VIC), a member of the vasoconstrictor ET peptide family, where ET-2 is the human orthologous peptide of the murine VIC. While ET-2/VIC gene expression has been observed in

Multi-layered Spatial Transcriptomics Identify Secretory Factors Promoting Human Hematopoietic Stem Cell Development.

Edie I Crosse et al.

Cell stem cell, 27(5), 822-839 (2020-09-19)

Hematopoietic stem cells (HSCs) first emerge in the embryonic aorta-gonad-mesonephros (AGM) region. Studies of model organisms defined intersecting signaling pathways that converge to promote HSC emergence predominantly in the ventral domain of the dorsal aorta. Much less is known about

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