SAE0219

Mucin Degradation Enzyme

for preparative digestions, powder

Propriétés

• Niveau de qualité: 200
• Forme: powder
• Durée de conservation: 2 yr (retest)
• Conditions de stockage: protect from light
• Conditions d'expédition: dry ice
• Température de stockage: -10 to -25°C

Description

Description générale

Mucin Degradation Enzyme is a metalloprotease useful for digesting heavily O-glycosylated mucin proteins. This product is made for preparative scale digestions of viscous material that is dense with mucin-type glycoproteins.

Application

For use as a sample preparation tool in research and discovery. Used for proteolytic degradation of mucin-dense tissues to allow for downstream processing.

Actions biochimiques/physiologiques

The Mucin Degradation enzyme is a mutated form of a protease that specifically recognizes densely glycosylated mucins and mucin-domains, and proteolytically cleaves the peptide backbone. In nature this presumably enhances the virulence of the pathogenic microbe, but in the laboratory is a useful way of accessing molecular structures in tissues normally shielded by mucins.

Informations sur la sécurité

• Code de la classe de stockage: 13 - Non Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable