SAB5701881

Anti-Phospho-STK3/STK4-T180/T183 antibody produced in rabbit

• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.43

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: liquid
• Espèces réactives: mouse, rat, human
• Concentration: 1.46 mg/mL
• Technique(s): western blot: 1:500-1:2000
• Numéro d'accès UniProt: Q13188/Q13043
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: phosphorylation (pThr180/pThr183)

Description

Description générale

This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Immunogène

A phospho specific peptide corresponding to residues surrounding T180/T183 of human STK3/STK4.

Forme physique

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable