SAB4700594
Monoclonal Anti-CD90.2, azide free antibody produced in mouse
clone 1aG4/C5, purified immunoglobulin, buffered aqueous solution
Synonyme(s) :
Anti-Thy-1.2, Anti-Thy1
Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
About This Item
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
mouse
Conjugué
unconjugated
Forme d'anticorps
purified immunoglobulin
Type de produit anticorps
primary antibodies
Clone
1aG4/C5, monoclonal
Forme
buffered aqueous solution
Espèces réactives
mouse
Concentration
1 mg/mL
Technique(s)
flow cytometry: suitable
Isotype
IgG3
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Température de stockage
2-8°C
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
mouse ... Thy1(21838)
Catégories apparentées
Description générale
Cluster of differentiation 90.2 (CD90.2), also known as Thy-1.2, is a 25-37kDa GPI-anchored protein, encoded by the gene mapped to mouse chromosome 9. The protein is mainly localized on the external leaflet of the lipid bilayer and lipid rafts. The encoded protein is one of the allele of CD90 and is expressed primarily on murine T-cells.
The mouse monoclonal antibody 1aG4/C5 recognizes alloantigen Thy-1.2 of mouse Thy-1 (CD90); it does not cross-react with Thy-1.1 alloantigen. Thy-1 is an 18-35 kDa cell surface GPI linked glycoprotein (immunoglobulin superfamily); in mouse it is abundant on thymocytes and peripheral T lymphocytes.
Immunogène
thymocytes from C3H/Di mice (Thy-12 positive)
Application
The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 1 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
Actions biochimiques/physiologiques
Cluster of differentiation 90.2 (CD90.2) plays a major role in T-cell activation. In addition, it is also implicated in various nonimmunologic functions such as, inhibition of neurite outgrowth, apoptotic signaling, leukocyte and melanoma cell adhesion and migration, tumor suppression and fibroblast proliferation and migration. CD90. also acts as a tumor suppressor in ovarian cancer and nasopharyngeal carcinoma (NPC). Deficiency of CD90 is associated with the development of pulmonary fibrosis. The protein expressed in choroidal endothelial cells (CECs) modulates VEGF-mediated CEC activation and migration.
Caractéristiques et avantages
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Forme physique
Solution in azide free HEPES buffer, pH 7
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Outil de sélection de produits.
Code de la classe de stockage
10 - Combustible liquids
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
TGF-β1 epigenetically modifies Thy-1 expression in primary lung fibroblasts
Neveu WA
American Journal of Physiology. Cell Physiology, 309, C616-C626 (2015)
Thy-1 Regulates VEGF-Mediated Choroidal Endothelial Cell Activation and Migration: Implications in Neovascular Age-Related Macular Degeneration
Wang H
Investigative Ophthalmology & Visual Science, 57, 5525-5534 (2016)
Thy-1 as a regulator of cell-cell and cell-matrix interactions in axon regeneration, apoptosis, adhesion, migration, cancer, and fibrosis.
Rege TA and Hagood JS
Faseb Journal, 20, 1045-1054 (2006)
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
Contacter notre Service technique