SAB4300492

Anti-CDC2 (Ab-15) antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : Anti-CDC28A antibody produced in rabbit, Anti-CDK1 antibody produced in rabbit, Anti-DKFZp686L20222 antibody produced in rabbit, Anti-MGC111195 antibody produced in rabbit, Anti-cell division cycle 2, G1 to S and G2 to M antibody produced in rabbit
• Numéro MDL: MFCD00239719
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: ~34 kDa
• Espèces réactives: human, rat, mouse
• Concentration: 1 mg/mL
• Technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• Isotype: IgG
• Séquence immunogène: (G-T-Y-G-V)
• Numéro d'accès NCBI: NP_001163877.1
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... CDC2(983)

Description

Description générale

CDC2/CDK1 (cyclin-dependent kinase 1) belongs to the Ser/Thr protein kinase family. It is located on human chromosome 10q21.

Immunogène

Peptide sequence around aa. 13-17 (G-T-Y-G-V), according to the protein CDC2.

Actions biochimiques/physiologiques

CDC2/CDK1 (cyclin-dependent kinase 1) controls various mitotic processes like reorganization of the cytoskeleton, segregation of chromosome, formation and separation of daughter cells. It is essential for the multiplication of mammalian cell. It participates in tumorigenesis.

Caractéristiques et avantages

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Description de la cible

Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.

Forme physique

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable