SAB4300425

Anti-GRIN2B (Ab-1474) antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : Anti-MGC142178 antibody produced in rabbit, Anti-MGC142180 antibody produced in rabbit, Anti-NMDAR2B antibody produced in rabbit, Anti-NR2B antibody produced in rabbit, Anti-glutamate receptor, ionotropic, N-methyl D-aspartate 2B antibody produced in rabbit
• Numéro MDL: MFCD00243314
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: ~190 kDa
• Espèces réactives: human, rat, mouse
• Concentration: 1 mg/mL
• Technique(s): indirect immunofluorescence: 1:100-1:200
• Isotype: IgG
• Séquence immunogène: (H-V-Y-E-K)
• Numéro d'accès NCBI: NP_000825.2
• Numéro d'accès UniProt: Q13224
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... GRIN2B(2904)

Description

Description générale

GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) codes for N-methyl d-aspartate receptor subtype 2B (GluN2B). It belongs to the N-methyl-D-aspartate receptor (NMDAR) gene family. It is located on human chromosome 12p13.1.

Immunogène

Peptide sequence around aa. 1472-1476 (H-V-Y-E-K), according to the protein GRIN2B.

Actions biochimiques/physiologiques

GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) plays an important role in the growth of neurons and is highly essential for the learning and memory. GRIN2B mutation is associated with neuropsychiatric and developmental disorders like schizophrenia, Parkinson′s disease and bipolar disorder.

Caractéristiques et avantages

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Description de la cible

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.

Forme physique

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable