Epitope mapping has not been conducted, so the exact binding site is unknown. However, the immunogen is located at aa128-247 (Accession# P23560).
RAB0026
Human BDNF ELISA Kit
for serum, plasma, cell culture supernatant and urine
Synonyme(s) :
BDNF, Brain-derived neurotrophic factor
Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Sélectionner une taille de conditionnement
1 KIT
528,00 €
528,00 €
Check Cart for Availability
Sélectionner une taille de conditionnement
Changer de vue
1 KIT
528,00 €
About This Item
Code UNSPSC :
41116158
Nomenclature NACRES :
NA.32
528,00 €
Check Cart for Availability
Produits recommandés
Espèces réactives
human
Conditionnement
kit of 96 wells (12 strips x 8 wells)
Technique(s)
ELISA: suitable
capture ELISA: suitable
Entrée
sample type plasma
sample type serum
sample type cell culture supernatant(s)
sample type urine
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 80 pg/mL
standard curve range: 0.066-16 ng/mL
Méthode de détection
colorimetric
Conditions d'expédition
wet ice
Température de stockage
−20°C
Informations sur le gène
human ... BDNF(627)
Catégories apparentées
Description générale
The Human BDNF ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human BDNF in serum, plasma, cell culture supernatants and urine.
The brain derived neurotrophic factor (BDNF) gene is mapped to human chromosome 11p14.1.[1] BDNF is a member of the neurotrophin family of growth factors.[2] The gene encodes a precursor protein, proBDNF. Mature BDNF (mBDNF) is synthesized by post-translational cleavage of proBDNF. Both proBDNF and mBDNF play crucial roles in cellular signaling.[3]
Immunogène
Recombinant Human BDNF
Application
For research use only. Not for use in diagnostic procedures.
Human BDNF ELISA kit has been used to determine the effect of bone marrow mesenchymal stem cell (MSC) transplantation on BDNF protein expression in the striatum of Tourette syndrome (TS) rats.[4] It has also been used to determine the plasma BDNF levels in GD1 (Gaucher′s disease type 1) patients and control population.[5]
Human BDNF ELISA kit has been used to determine the effect of bone marrow mesenchymal stem cell (MSC) transplantation on BDNF protein expression in the striatum of Tourette syndrome (TS) rats.[4] It has also been used to determine the plasma BDNF levels in GD1 (Gaucher′s disease type 1) patients and control population.[5]
Actions biochimiques/physiologiques
Brain derived neurotrophic factor (BDNF) is involved in hippocampal function and verbal episodic memory in humans. Hence, variation in the BDNF gene expression alters these neurological functions.[9] BDNF also plays a vital role in vascular function and participates in angiogenesis via the specific receptor tropomyosin-related kinase B (TrkB).[10] It is involved in the pathogenesis of Alzheimer′s disease. ProBDNF interacts with p75 neurotrophin receptor, leading to long-term depression in the hippocampus.[3]
Autres remarques
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Composants de kit également disponibles séparément
Réf. du produit
Description
FDS
Mention d'avertissement
Warning
Mentions de danger
Conseils de prudence
Classification des risques
Met. Corr. 1
Code de la classe de stockage
8A - Combustible corrosive hazardous materials
Faites votre choix parmi les versions les plus récentes :
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Les clients ont également consulté
Shervin Pejhan et al.
Frontiers in cell and developmental biology, 8, 763-763 (2020-09-26)
Rett Syndrome (RTT) is a rare and progressive neurodevelopmental disorder that is caused by de novo mutations in the X-linked Methyl CpG binding protein 2 (MECP2) gene and is subjected to X-chromosome inactivation. RTT is commonly associated with neurological regression
Oxidative Stress-Tolerant Stem Cells from Human Exfoliated Deciduous Teeth Decrease Hydrogen Peroxide-Induced Damage in Organotypic Brain Slice Cultures from Adult Mice
Xiao L, et al.
International Journal of Molecular Sciences, 20(8), 1858-1858 (2019)
Hélio José Coelho-Júnior et al.
International journal of environmental research and public health, 17(10) (2020-05-20)
The present study compared the effects of traditional resistance training (TRT) and combined power training (PT) and TRT (PTRT) on cognitive parameters and serum brain-derived neurotrophic factor (BDNF) levels in non-demented, well-functioning, community-dwelling older women. Forty-five older women were randomized
Zuzana Paduchová et al.
Nutrients, 13(4) (2021-04-04)
In the DEPOXIN project, we have found that a high ratio of omega-6/omega-3 fatty acids (FA) is associated with worsening of depressive symptoms in children and adolescents with depressive disorder (DD) and that the 12-week omega-3 FA supplementation modulates DD
Xiumei Liu et al.
Experimental and therapeutic medicine, 11(4), 1211-1216 (2016-04-14)
The aim of the present study was to investigate the effect of bone marrow mesenchymal stem cell (MSC) transplantation on brain-derived neurotrophic factor (BDNF) expression in the striatum of Tourette syndrome (TS) rats. In addition, the possible mechanism of MSC
-
Could you please confirm if this kit is capable of recognizing both free and bound BDNF?
1 réponse-
Utile ?
-
Filtres actifs
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
Contacter notre Service technique
