R9404

Anti-RhoA antibody produced in rabbit

~2 mg/mL, affinity isolated antibody, buffered aqueous solution

• Synonyme(s) : Anti-p21 Rho
• Numéro MDL: MFCD09265373
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen ~21 kDa
• Espèces réactives: monkey, mouse, human
• Concentration: ~2 mg/mL
• Technique(s): western blot: 1-2 μg/mL using HEK293 cells expressing human RhoA/ Hela cell extract
• Numéro d'accès UniProt: P61586
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... RHOA(387)

Description

Description générale

RhoA (ras homolog family member A) belongs to the Rho GTPase family of proteins. It is located on chromosome 3p21.31.

Spécificité

Anti-RhoA recognizes human RhoA.

Immunogène

synthetic peptide corresponding to amino acids 177-189 located near the C-terminus of human RhoA.

Actions biochimiques/physiologiques

In multiciliated epithelial cells, RhoA (ras homolog family member A) controls the actin network dynamics. It also modulates membrane protrusion and contractility in the cell body. It is one of the essential factor for Ras transformation. It is associated with cancer metastasis.

Forme physique

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Stockage et stabilité

For extended storage, freeze in working aliquots at –20 °C. Repeated freezing and thawing, or storage in "frost-free" freezer, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours. For continuous use, store at 2-8°C for up to one month.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)