PLA0108

Rabbit anti-DDB1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Synonyme(s) : 127kDa, DDB p127 subunit, DDBA, DNA damage-binding protein a, Damage-specific DNA-binding protein 1, HBV X-associated protein 1, UV-DDB 1, UV-DDB1, UV-damaged DNA-binding factor, UV-damaged DNA-binding protein 1, XAP-1, XAP1, XPCE, XPE, XPE-BF, XPE-binding factor, damage-specific DNA binding protein 1, damage-specific DNA binding protein 1 (127kD), xeroderma pigmentosum group E-complementing protein
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Espèces réactives: human, mouse
• Concentration: 0.2 mg/mL
• Technique(s): immunohistochemistry: 1:500- 1:2,000; immunoprecipitation (IP): 2-5 μg/mg; western blot: 1:1,000- 1:10,000
• Numéro d'accès: Q13289
• Numéro d'accès UniProt: Q16531
• Conditions d'expédition: wet ice
• Température de stockage: 2-8°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: rabbit ... DDB1(1642)

Description

Immunogène

The epitope recognized by PLA0108 maps to a region between residue 1100 and the C-terminus (residue 1140) of human damage-specific DNA binding protein 1 using the numbering given in TrEMBL entry Q13289 (GeneID 1642).

Forme physique

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Autres remarques

DDB1 (DNA Damage Binding Protein 1) is a subunit of the DNA damage-binding protein complex (DDB) involved in DNA repair. As part of a complex with Cul4-based ubiquitin ligase, Cul4-Ddb1 can directly modify chromatin through the ubiquitination of histones as well as ubiquitinate other chromatin bound factors. A deficiency in Cul4-Ddb1 ubiquitin ligase has been associated with xeroderma pigmentosum, a heritable disease characterized by defects in nucleotide excision repair and skin cancer development.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable