P7002

Phospho(enol)pyruvic acid trisodium salt hydrate

≥97% (enzymatic), powder

• Synonyme(s) : 2-(Phosphonooxy)-2-propenoic acid trisodium salt, PEP
• Formule linéaire : C₃H₂O₆PNa₃ · x H₂O
• Numéro CAS: 5541-93-5
• Poids moléculaire : 233.99 (anhydrous basis)
• Numéro MDL: MFCD00150734
• Code UNSPSC : 12352204
• ID de substance PubChem : 24898810
• Nomenclature NACRES : NA.32

Propriétés

• Nom du produit: Phospho(enol)pyruvic acid trisodium salt hydrate, ≥97% (enzymatic)
• Niveau de qualité: 200
• Essai: ≥97% (enzymatic)
• Forme: powder
• Solubilité: water: 100 mg/mL, clear to slightly hazy, colorless to very faintly yellow
• Température de stockage: −20°C
• Chaîne SMILES: [Na].OC(=O)C(=C)OP(O)(O)=O
• InChI: 1S/C3H5O6P.Na.H/c1-2(3(4)5)9-10(6,7)8;;/h1H2,(H,4,5)(H2,6,7,8);;
• Clé InChI: KZPUEZVJSLLABH-UHFFFAOYSA-N

Description

Application

Phospho(enol)pyruvic acid trisodium salt hydrate has been used in:

• several enzyme activity assays, such as PRPP synthetase (PRPPS) assay[1], ribokinase (RK) assay[1], adenine phosphoribosyltransferase (APRT) assay[1]
• in the reaction mixture for enzyme kinetic assay to determine platelet-derived growth factor receptor α (PDGFRA) kinetic parameters[2]
• as a component in buffer B to react with adenosine diphosphate (ADP) to form adenosine triphosphate (ATP) for energy charge measurement[3]

Actions biochimiques/physiologiques

Phosphoenolpyruvic acid plays a major role in the initial step of glycolysis by acting as an inhibitor of hexokinase, phosphoglucose isomerase, phosphofructokinase and aldolase.[4]

Phospho(enol)pyruvic acid (PEP) is involved in glycolysis and gluconeogenesis. In glycolysis, PEP is metabolized by pyruvate kinase to yield pyruvate. In plants, PEP is involved in the formation of aromatic amino acids as well as in the carbon fixation pathway.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)