P4997
Anti-Potassium Channel KCa3.1 (Intermediate-conductance Ca2+-activated Potassium Channel 4) antibody produced in rabbit
affinity isolated antibody, lyophilized powder
Synonyme(s) :
Anti-IKCa1, Anti-KCNN4, Anti-SK4
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50 μL
326,00 €
200 μL
783,00 €
326,00 €
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Changer de vue
50 μL
326,00 €
200 μL
783,00 €
About This Item
326,00 €
Check Cart for Availability
Produits recommandés
Source biologique
rabbit
Niveau de qualité
Conjugué
unconjugated
Forme d'anticorps
affinity isolated antibody
Type de produit anticorps
primary antibodies
Clone
polyclonal
Forme
lyophilized powder
Espèces réactives
human, rat, mouse (predicted)
Technique(s)
western blot: 1:200
Numéro d'accès UniProt
Conditions d'expédition
dry ice
Température de stockage
−20°C
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... KCNN4(3783)
mouse ... Kcnn4(16534)
rat ... Kcnn4(65206)
Immunogène
synthetic peptide corresponding to amino acid residues 350-363 of rat KCa3.1. The sequence has 100% homology with human, mouse, and pig.
Application
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Western Blotting (1 paper)
Immunofluorescence (1 paper)
Western Blotting (1 paper)
Forme physique
Lyophilized powder from phosphate buffered saline containing 1% bovine serum albumin and 0.05% sodium azide.
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Valentina Back et al.
Journal of thrombosis and haemostasis : JTH, 20(11), 2587-2600 (2022-07-23)
Within the vasculature platelets and endothelial cells play crucial roles in hemostasis and thrombosis. Platelets, like endothelial cells, possess intermediate conductance Ca2+ -activated K+ (IKCa ) channels and generate nitric oxide (NO). Although NO limits platelet aggregation, the role of
Eva M Grössinger et al.
Journal of immunology (Baltimore, Md. : 1950), 200(2), 749-757 (2017-12-17)
In inflammatory arthritis, the dysregulation of osteoclast activity by proinflammatory cytokines, including TNF, interferes with bone remodeling during inflammation through Ca2+-dependent mechanisms causing pathological bone loss. Ca2+-dependent CREB/c-fos activation via Ca2+-calmodulin kinase IV (CaMKIV) induces transcriptional regulation of osteoclast-specific genes
Lee-Way Jin et al.
Annals of clinical and translational neurology, 6(4), 723-738 (2019-04-26)
Microglia play a pivotal role in the initiation and progression of Alzheimer's disease (AD). We here tested the therapeutic hypothesis that the Ca2+-activated potassium channel KCa3.1 constitutes a potential target for treating AD by reducing neuroinflammation. To determine if KCa3.1
Yi-Je Chen et al.
PloS one, 8(11), e81006-e81006 (2013-12-07)
Allograft vasculopathy (AV) remains one of the major challenges to the long-term functioning of solid organ transplants. Although its exact pathogenesis remains unclear, AV is characterized by both fibromuscular proliferation and infiltration of CD4(+) memory T cells. We here tested
Katy M Roach et al.
PloS one, 8(12), e85244-e85244 (2014-01-07)
Idiopathic pulmonary fibrosis (IPF) is a common, progressive and invariably lethal interstitial lung disease with no effective therapy. We hypothesised that K(Ca)3.1 K(+) channel-dependent cell processes contribute to IPF pathophysiology. K(Ca)3.1 expression in primary human lung myofibroblasts was examined using
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