N7632
N-Nitrosodiethanolamine
Synonyme(s) :
2,2′-(Nitrosoimino)bisethanol, N,N-Diethanolnitrosamine, Bis(2-hydroxyethyl)nitrosamine, NDELA
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About This Item
Formule empirique (notation de Hill):
C4H10N2O3
Numéro CAS:
Poids moléculaire :
134.13
Numéro Beilstein :
1762620
Numéro MDL:
Code UNSPSC :
12352116
ID de substance PubChem :
Nomenclature NACRES :
NA.25
Produits recommandés
Forme
liquid
Impuretés
≤10% Isopropanol
Température de stockage
2-8°C
Chaîne SMILES
OCCN(N=O)CCO
InChI
1S/C4H10N2O3/c7-3-1-6(5-9)2-4-8/h7-8H,1-4H2
Clé InChI
YFCDLVPYFMHRQZ-UHFFFAOYSA-N
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Application
- Changes in levels of N-nitrosamine formed from amine-containing compounds during chloramination via photocatalytic pretreatment with immobilized TiO(2): Effect of source water and pH.: In this study, NDELA is used as a standard to examine how the formation of nitrosamines, such as N-Nitrosodiethanolamine, is affected by different water sources and pH levels during water treatment processes (Seid et al., 2022).
- Monitoring and risk assessment of hazardous chemicals in toy-slime and putty in the Netherlands.: This research focuses on the presence of N-Nitrosodiethanolamine in children′s toys, providing important data for consumer safety and regulatory standards (Braver et al., 2021).
- On-line solid phase extraction-ultra-high performance liquid chromatography coupled to tandem mass spectrometry for the determination of N-nitrosodiethanolamine in baby shampoo.: Highlights the usage of N-Nitrosodiethanolamine as an analytical standard in application of advanced chromatographic techniques for detecting harmful substances in consumer products, ensuring product safety and regulatory compliance (Tada et al., 2021).
Mention d'avertissement
Danger
Mentions de danger
Conseils de prudence
Classification des risques
Carc. 1B - Flam. Liq. 2
Code de la classe de stockage
3 - Flammable liquids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
52.9 °F
Point d'éclair (°C)
11.6 °C
Équipement de protection individuelle
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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Les clients ont également consulté
Michelle K Dennehy et al.
Chemical research in toxicology, 18(3), 556-565 (2005-03-22)
N-Nitrosodiethanolamine (NDELA) is a bident carcinogen that undergoes both P-450 mediated alpha-hydroxylation and beta-oxidation, leading ultimately to the formation of two prominent DNA adducts, glyoxaldeoxyguanosine (gdG) and O6-2-hydroxyethyldeoxyguanosine (OHEdG), in rat liver. HPLC coupled with electrospray ionization (ESI) and tandem
M Futakuchi et al.
Cancer letters, 106(2), 263-269 (1996-09-10)
Potential synergism between four N-nitroso compounds (nitrosomorpholine, nitrosodimethylamine, nitrosodiethanolamine, nitroso-oxazolidine) in rat liver carcinogenesis was examined in the medium-term bioassay. Male F344 rats were initially given diethylnitrosamine (DEN, 200 mg/kg, ip) and beginning 2 weeks later received test chemicals for
R C Schothorst et al.
Analytical and bioanalytical chemistry, 381(3), 681-685 (2005-01-26)
We have developed and validated in-house a liquid chromatography and mass spectrometry (LC-MS-MS) method for determination of N-nitrosodiethanolamine (NDELA) in cosmetics. The sample is diluted with water and then a C18 clean-up is performed. The average recovery of NDELA is
Richard N Loeppky et al.
Chemical research in toxicology, 15(4), 470-482 (2002-04-16)
The mechanism by which environmentally prevalent N-nitrosodiethanolamine (NDELA) and related 2-hydroxyethyl- or other beta-oxidized nitrosamines initiate the carcinogenic process has remained obscure. (32)P-Postlabeling assays for the pH sensitive glyoxal-deoxyguanosine (gdG) and the O(6)-2-hydroxyethyldeoxyguanosine (OHEdG) DNA adducts have been developed as
R Hasegawa et al.
Cancer letters, 123(2), 185-191 (1998-03-07)
Complete carcinogens must possess both initiating and promoting properties. Most N-nitroso compounds are mutagens and are considered to be initiators, but some are not mutagenic and yet are complete carcinogens. To investigate the two activities, brief treatments of male F344
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