M6309

Anti-Matrix Metalloproteinase-23, Hinge Region antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

• Synonyme(s) : Anti-MMP-23
• Numéro MDL: MFCD03097011
• Code UNSPSC : 12352203

Propriétés

• Source biologique: rabbit
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous glycerol solution
• Poids mol.: antigen (active form) 45 kDa; antigen (pro-form) 58 kDa
• Espèces réactives: human
• Concentration: ~1 mg/mL
• Technique(s): immunohistochemistry (frozen sections): suitable; immunoprecipitation (IP): suitable; indirect ELISA: suitable; western blot: 1:1,000
• Numéro d'accès UniProt: P50281
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... MMP14(4323)

Description

Description générale

Matrix metalloproteinase-23B (MMP-23B) possesses regions which are rich in amino acids like proline and cysteine. The MMP-23B gene is localized on human chromosome 1p36.

Spécificité

Reacts with reduced and non-reduced MMP-23. Recognizes the pro-form and active forms of MMP-23 as well as a series of further cleaved active forms.

Immunogène

synthetic peptide corresponding to the hinge region of human matrix metalloproteinase-23 (MIFR-2, CA-MMP).

Actions biochimiques/physiologiques

Matrix metalloproteinase-23B (MMP-23B) is part of the matrix metalloproteinase family of proteins, which take part in the remodeling of the extracellular matrix.

Forme physique

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide.