L7635

L-α-Lysophosphatidylinositol sodium salt from Glycine max (soybean)

≥96%

• Synonyme(s) : 1-Acyl-sn-glycero-3-phospho-(1-D-myo-inositol)
• UNSPSC Code: 51191904
• NACRES: NA.25
• MDL number: MFCD00131447

Propriétés

• biological source: soybean
• Quality Segment: 200
• assay: ≥96%
• form: powder
• functional group: phospholipid
• lipid type: phosphoglycerides
• shipped in: ambient
• storage temp.: −20°C

Description

Application

L-α-Lysophosphatidylinositol sodium salt from Glycine max (soybean) has been used as an agonist of G protein-coupled receptor 55 (GPR55).

Biochem/physiol Actions

L-α-Lysophosphatidylinositols (LPI) functions as an endogenous ligand for putative cannabinoid receptor and G protein-coupled receptor 55 (GPR55). LPI plays a regulatory role in cell proliferation, migration and function. Increased circulatory levels of LPI has been observed in the obese patients. In addition, overexpression of LPI leads to the development of various types of cancers including ovarian and breast cancer. LPI can be used as a potential diagnostic and prognostic biomarker for ovarian cancer.

L-α-Lysophosphatidylinositols from Glycine max (soybean) are enriched with stearate and palmitate. Soybean Lysophosphatidylinositols may be compared with other lysophosphatidylinositol for biological activities which depend upon the identity of the acylated fatty acid.

Preparation Note

Prepared by the action of phospholipase A on L-α-phosphatidylinositol.

Analysis Note

Contains primarily palmitic and stearic acids.

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• EPI (équipement de protection individuelle): Eyeshields, Gloves, type N95 (US)