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I6005

Sigma-Aldrich

myo-Inositol hexasulfate hexapotassium salt

Synonyme(s) :

Inositol hexakissulfate, InsS6

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About This Item

Formule linéaire :
C6H6O24S6K6
Numéro CAS:
28434-25-5
Poids moléculaire :
889.08
Numéro MDL:
MFCD00055894
Code UNSPSC :
12352201
ID de substance PubChem :
24896081

Température de stockage

−20°C

Chaîne SMILES 

[K].OS(=O)(=O)OC1C(OS(O)(=O)=O)C(OS(O)(=O)=O)C(OS(O)(=O)=O)C(OS(O)(=O)=O)C1OS(O)(=O)=O

InChI

1S/C6H12O24S6.K.H/c7-31(8,9)25-1-2(26-32(10,11)12)4(28-34(16,17)18)6(30-36(22,23)24)5(29-35(19,20)21)3(1)27-33(13,14)15;;/h1-6H,(H,7,8,9)(H,10,11,12)(H,13,14,15)(H,16,17,18)(H,19,20,21)(H,22,23,24);;

Clé InChI

JYVHCOUFXHFSLT-UHFFFAOYSA-N

Actions biochimiques/physiologiques

InsS6 has a molecular footprint and negative surface charge that is similar to that of phytic acid (InsP6), but with lower biological activity. It is used as a control in studies of the cellular actions of phytic acid. It is also a competitive inhibitor of Aspergillus phytase.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Aaron J Oakley
Biochemical and biophysical research communications, 397(4), 745-749 (2010-06-15)
Phytases hydrolyse the phosphomonoesters of phytate (myo-inositol-1,2,3,4,5,6-hexakis phosphate) and thus find uses in plant and animal production through the mobilisation of phosphorus from this source. The structure of partially deglycosylated Aspergillus niger PhyA is presented in apo form and in
J W Wyse et al.
Biochemical and biophysical research communications, 144(2), 779-786 (1987-04-29)
Previous biophysical investigations, including those from our laboratories, have reported that polyphosphates weaken RBC membrane skeletal protein-protein interactions and decrease hemoglobin affinity for oxygen. We have additionally demonstrated that low-affinity intact RBC's may be produced by inositol hexaphosphate (IHP) incorporation
T Otake et al.
Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 63(7), 676-683 (1989-07-01)
The monosaccharide substances inositol hexasulfate (IHS) and inositol hexaphosphoric acid (Phytic acid, IHP) were investigated for their antiviral effect on the human immunodeficiency virus (HIV) in vitro. In MT-4 cells IHS completely inhibited the cytopathic effect of HIV and the
A Romero et al.
European journal of biochemistry, 241(2), 453-461 (1996-10-15)
Acidic fibroblast-growth factor (aFGF) is one of the typical members of a group of nine polypeptides of relatively similar amino acid sequence known as the fibroblast-growth-factor family of proteins. Widely distributed throughout the organism, fibroblast-growth factors seem to be involved
J M Dabora et al.
The Journal of biological chemistry, 266(35), 23637-23640 (1991-12-15)
Acidic fibroblast growth factor (aFGF) is unstable at physiological temperatures in the absence of polyanions such as heparin. Therefore, the effect of temperature on the kinetics of refolding of aFGF has been examined in the presence and absence of several
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