Immunogen Sequence: GI # 20986497, sequence 341-570
Recombinant mitogen-activated protein kinase 7 isoform 1
Application
Anti-MAPK7 (ab2) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Actions biochimiques/physiologiques
Mitogen-activated protein kinase 7 (also known as MAP kinase 7) is an enzyme encoded by the MAPK7 gene in humans and is mapped to chromosome 17 band p11.2. It belongs to mitogen-activated protein kinase (MAPK) family and regulates a wide variety of cellular processes such as proliferation, differentiation, necrosis, apoptosis and degeneration. MAPK7 is involved in degeneration of nucleus pulposus. Expression of MAPK7 may act as a valuable indicator for predicting lung cancer risk in smokers.
Forme physique
Solution in phosphate buffered saline containing 0.02% sodium azide.
Biochemical and biophysical research communications, 449(4), 466-470 (2014-05-27)
Extracellular-signal-regulated kinase 5 (ERK5) is a member of the mitogen-activated protein kinase (MAPK) family and regulates a wide variety of cellular processes such as proliferation, differentiation, necrosis, apoptosis and degeneration. However, the expression of ERK5 and its role in degenerated
Mitogen/extracellular signal-regulated kinase-5 (MEK5)/extracellular signal-regulated protein kinase-5 (ERK5) pathway plays a pro-oncogenic role in tumourigenesis by anticell apoptosis, promoting cell proliferation and differentiation in response to extracellular stimuli. As overexpressed MEK5/ERK5 is involved in the development of lung cancer, we
Assignment of big MAP kinase (PRKM7) to human chromosome 17 band p11.2 with somatic cell hybrids.
S M Purandare et al.
Cytogenetics and cell genetics, 83(3-4), 258-259 (1999-03-11)
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Filtres actifs
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