Accéder au contenu
Merck
Toutes les photos(1)

Principaux documents

Voir toute la documentation

G0897

Sigma-Aldrich

Genistin

from Glycine max (soybean), ≥95% (HPLC)

Synonyme(s) :

4′,5,7-Trihydroxyisoflavone 7-glucoside, Genistein 7-glucoside, Genistein-7-O-β-D-glucopyranoside, Genistoside, NSC 5112

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme

Sélectionner une taille de conditionnement

1 MG
67,20 €
5 MG
235,00 €

67,20 €

Check Cart for Availability
Devis pour commande en gros
Toutes les photos(1)

Sélectionner une taille de conditionnement

Changer de vue
1 MG
67,20 €
5 MG
235,00 €

About This Item

Formule empirique (notation de Hill) :
C21H20O10
Numéro CAS:
529-59-9
Poids moléculaire :
432.38
Beilstein:
64479
Numéro MDL:
MFCD00016883
Code UNSPSC :
12352200
ID de substance PubChem :
24895028
Nomenclature NACRES :
NA.77

67,20 €

Check Cart for Availability
Devis pour commande en gros

Source biologique

Glycine max (soybean)

Niveau de qualité

200

Essai

≥95% (HPLC)

Solubilité

DMSO: 10 mg/mL

Température de stockage

−20°C

Chaîne SMILES 

OC[C@H]1O[C@@H](Oc2cc(O)c3C(=O)C(=COc3c2)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C21H20O10/c22-7-15-18(26)19(27)20(28)21(31-15)30-11-5-13(24)16-14(6-11)29-8-12(17(16)25)9-1-3-10(23)4-2-9/h1-6,8,15,18-24,26-28H,7H2/t15-,18-,19+,20-,21-/m1/s1

Clé InChI

ZCOLJUOHXJRHDI-CMWLGVBASA-N

Vous recherchez des produits similaires ? Visite Guide de comparaison des produits

Application

Genistin has been used for immune reactivity against influenza viruses in vitro[1] and as an internal standard in isoflavones quantification.[2]

Actions biochimiques/physiologiques

Inactive analog of genistein; useful as a negative control for genistein and other tyrosine kinase inhibitors.
Selective inhibitor of mammalian terminal deoxynucleotidyl transferase (TdT), with no measurable effect on mammalian or microbial DNA polymerases.

Caractéristiques et avantages

This compound is featured on the Dopamine and Norepinephrine Metabolism and Histamine Synthesis and Metabolism pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number
0000223696
0000223696
0000189651
0000168610
0000168609

Vous ne trouvez pas la bonne version ?

Si vous avez besoin d'une version particulière, vous pouvez rechercher un certificat spécifique par le numéro de lot.

Rechercher un(e) COA

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Les clients ont également consulté

Slide 1 of 8

1 of 8

Genistein analytical standard

Supelco

92136

Genistein

Daidzin analytical standard

Supelco

42926

Daidzin

Glycitein analytical standard

Supelco

43534

Glycitein

Glycitin United States Pharmacopeia (USP) Reference Standard

USP

1295855

Glycitin

Daidzein analytical standard

Supelco

16587

Daidzein

Genistein, Soybean A cell-permeable, reversible, substrate competitive inhibitor of protein tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC₅₀ = 2.6 µM).

Sigma-Aldrich

345834

Genistein, Soybean

Genistein primary reference standard

05360590

Genistein

Genistein Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1859

Genistein

T Hamakawa et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 19(21), 9306-9312 (1999-10-26)
Neurotrophic factors have well established roles in neuronal development and adult synaptic plasticity, but their precise role in synapse formation has yet to be determined. This paper provides the first direct evidence that neurotrophic factors in brain conditioned medium (CM)
Soy saponins meditate the progression of colon cancer in rats by inhibiting the activity of beta-glucuronidase and the number of aberrant crypt foci but not cyclooxygenase-2 activity.
Guo YW, et al.
ISRN Oncology, 2013 (2013)
Zong-Ping Zheng et al.
Food & function, 2(5), 259-264 (2011-07-23)
The phytochemcal profiles of Cudrania cochinchinensis leaf, twig, stem and root were compared by HPLC analysis. It was found that C. cochinchinensis stem extract contained some unknown natural products with potential tyrosinase inhibitory activities. Therefore, the chemical constitutes in extract
Amélia P Rauter et al.
Phytotherapy research : PTR, 24 Suppl 2, S133-S138 (2010-03-24)
The antihyperglycaemic effect of eight standard flavonoids, previously identified in the ethanol extract of the claimed antidiabetic plant Genista tenera, was evaluated on streptozotocin (STZ)-induced diabetic Wistar rats. The aglycones apigenin, chrysoeriol and genistein, the monoglucosides apigenin 7-O-glucoside, luteolin 7-O-glucoside
Bishnu Prasad Pandey et al.
Enzyme and microbial technology, 48(4-5), 386-392 (2011-11-25)
Screening of cytochrome P450 monoxygenases responsible for the regiospecific hydroxylation of flavones, isoflavones and chalcones was attempted using a P450 library constructed from Streptomyces avermitilis MA4680, Bacillus and Nocardia farcinica IFM10152 strains. As electron transfer redox partners with the P450s
Afficher tous les articles scientifiques apparentés

Articles

Serotonin Synthesis & Metabolism

Serotonin is stored in cells and metabolized by MAO, influencing CNS, GI, and platelet functions.

Questions

1–2 sur 2 questions  

  1. What is the lambda max for genistin and what is the molar extinction coefficient at that wavelength?

    1 réponse

    1. We have data from our QC labs here at Sigma on one of the Genistin products we offer, G0897. The solvent is 85% ethanol/15% water, and the lambda max is typically 262.0 or 262.5 nm. We measured the molar extinction coefficients at the lambda max for four different lots of G0897 back in the 1990s, and the average value was 39,800 M-1.Genistin is a derivative of Genistein. There is an entry for Genistein in the chemicals encyclopedia published by the Royal Society of Chemistry, with information for Genistin under that heading.According to the chemicals encyclopedia published by the Royal Society of Chemistry, 14th edition, entry #4391, uv max (85% ethanol) 262.5 nm (a 90.5)".The value of ""a 90.5"" is the same as an E0.1%, or the extinction coefficient for a 1 mg/mL (or 1 gram per Liter) solution.If one multiplies 90.5 (L/g) by the molecular weight of genistin (432.38 g/mole), you get 39,130 M-1. This is pretty close to the value of 39,800 from our data above."

      Utile ?

  2. What is the Department of Transportation shipping information for this product?

    1 réponse

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Utile ?

Évaluations

Aucune valeur de notation

Filtres actifs

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique