Solution stability has not been determined for this product, however commercial and pharmaceutical preparations are cited as being stable at room temperature for up to 18 months, protected from light. Folic acid is also a component of most of the classical DMEM media formulations, for example D5546. These products are also assigned a shelf life of 18 months, but are stored at 2 - 8 deg. C. Storing at -20 deg. C may or may not extend the shelf life. There is a possibility that the freeze/thaw process may result in precipitation and may be detrimental.
F8758
Folic acid
BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥97%
Synonyme(s) :
Pterylmonoglutamic acid, PteGlu, Pteroyl-L-glutamic acid, Vitamin M
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About This Item
Produits recommandés
Source biologique
synthetic
Niveau de qualité
Gamme de produits
BioReagent
Essai
≥97%
Forme
powder
Poids mol.
Mw 441.40 g/mol
Technique(s)
cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable
Couleur
dark yellow
Solubilité
1 M NaOH: soluble 50 mg/mL, clear to very slightly hazy, faintly yellow to dark yellow-orange
Température de stockage
room temp
Chaîne SMILES
NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O
InChI
1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
Clé InChI
OVBPIULPVIDEAO-LBPRGKRZSA-N
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Description générale
Application
Actions biochimiques/physiologiques
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 1
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
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Articles
Explore folic acid importance in serum-free eukaryotic cell cultures, including CHO cells, and its role in media supplementation.
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Is it better to store folic acid (Product No. F8758) solution at RT or -20'C? Also, how long is it stable as a solution for at recommended temperature?
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Is Product No. F8758, Folic Acid, tested for endotoxins?
1 réponse-
No, Product No. F8758 has not been tested for endotoxins. This product has, however, been tested for use in mammalian cell culture and insect cell culture.
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What is the Department of Transportation shipping information for this product?
1 réponse-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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What is the stability of folic acid (Product No. F8758) once in solution?
1 réponse-
This product is photolabile and is inactivated by UV light. Alkaline solutions are reasonably stable in the dark, but heating will destroy both alkaline and acidic solutions.
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What is the solubility of folic acid (Product No. F8758)?
1 réponse-
Product No. F8758 is soluble in 1 M NaOH (50 mg/mL). The free acid is only slightly soluble in water (0.01 mg/mL at 0 °C), and is insoluble in aqueous solutions below pH 5. It is soluble in sodium bicarbonate or sodium hydroxide solutions.
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