The solubility has been tested at 10mg/mL in 0.1M Boric acid, resulting in a white haze.
C9801
Casein, N,N-dimethylated from bovine milk
essentially salt-free, lyophilized powder
Synonyme(s) :
N,N-dimethylcasein
Se connecter pour consulter les tarifs organisationnels et contractuels.
Sélectionner une taille de conditionnement
Changer de vue
| À vous/Référence | Disponibilité | Prix |
|---|---|---|
1 g | Vérifier la disponibilité des articles du panier | 81,00 € |
5 g | Vérifier la disponibilité des articles du panier | 401,00 € |
25 g | Vérifier la disponibilité des articles du panier | 1 190,00 € |
50 g | Vérifier la disponibilité des articles du panier | 2 090,00 € |
A propos de cet article
Form:
essentially salt-free, lyophilized powder
Assay:
≥90% (colorimetric)
Biological source:
bovine milk
81,00 €
Vérifier la disponibilité des articles du panier
Service technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aiderbiological source
bovine milk
Quality Segment
assay
≥90% (colorimetric)
form
essentially salt-free, lyophilized powder
technique(s)
activity assay: suitable
storage temp.
−20°C
SMILES string
[P](=O)(OCC(NC(=O)C(NC(=O)C(N)Cc1ccccc1)CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(C(O)C)C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(C
InChI
1S/C81H125N22O39P/c1-36(2)31-50(76(132)94-43(15-24-57(87)108)71(127)101-52(34-64(120)121)78(134)98-49(81(137)138)11-7-8-30-82)99-72(128)47(19-28-61(114)115)95-77(133)51(33-63(118)119)100-73(129)48(20-29-62(116)117)97-80(136)65(37(3)104)103-75(131)44(16-25-58(88)109)92-68(124)42(14-23-56(86)107)90-67(123)41(13-22-55(85)106)91-69(125)45(17-26-59(110)111)93-70(126)46(18-27-60(112)113)96-79(135)53(35-142-143(139,140)141)102-74(130)40(12-21-54(84)105)89-66(122)39(83)32-38-9-5-4-6-10-38/h4-6,9-10,36-37,39-53,65,104H,7-8,11-35,82-83H2,1-3H3,(H2,84,105)(H2,85,106)(H2,86,107)(H2,87,108)(H2,88,109)(H,89,122)(H,90,123)(H,91,125)(H,92,124)(H,93,126)(H,94,132)(H,95,133)(H,96,135)(H,97,136)(H,98,134)(H,99,128)(H,100,129)(H,101,127)(H,102,130)(H,103,131)(H,110,111)(H,112,113)(H,114,115)(H,116,117)(H,118,119)(H,120,121)(H,137,138)(H2,139,140,141)
InChI key
BECPQYXYKAMYBN-UHFFFAOYSA-N
Gene Information
bovine ... CSN1S1(282208), CSN1S2(282209), CSN2(281099), CSN3(281728)
General description
Casein is a milk protein, that is not expensive and nontoxic. highly stable. This phosphoproteins accounts for 80% of the total protein present in bovine milk. Casein is a member of one of the larger family of secretory calcium?binding phosphoproteins.
Application
Casein, N,N-dimethylated from bovine milk can be used in assays to detect and help determine the functional role of tissue transglutaminase (tTG) in disease. In particular, Casein, N,N-dimethylated has been used in the mechanic and kinetic analysis of tTG on protein substrates, which may be linked to neurodegenerative disease.
This preparation has less than 10% reactivity with 2,4,6-trinitrobenzenesulfonic acid (TNBS) compared to non-methylated casein.
Protease substrate that has been used to assay basilase[1] and a subtilisin analog that had been produced by site-directed mutagenesis.[2]
This preparation has less than 10% reactivity with 2,4,6-trinitrobenzenesulfonic acid (TNBS) compared to non-methylated casein.
Protease substrate that has been used to assay basilase[1] and a subtilisin analog that had been produced by site-directed mutagenesis.[2]
Casein, N,N-dimethylated from bovine milk has been used:
- in the determination of general proteolytic activity
- as a substrate to study the effect of dephosphorylation on the calcium-activated neutral proteases (CANP) proteolysis of paired helical filaments (PHF) II-τ
- in transglutaminase (TG) assay
Biochem/physiol Actions
Casein is highly preferred as a drug delivery vehicle. It possess antioxidant activity.
Preparation Note
Reductive methylation of C5890 by the method of Cabacungan, J.C., et al., Anal. Biochem., 124, 272 (1982).
1 of 1
Cet article | |||
|---|---|---|---|
| assay ≥90% (colorimetric) | assay - | assay ≥85% (biuret) | assay - |
| technique(s) activity assay: suitable | technique(s) activity assay: suitable, electrophoresis: suitable, immunocytochemistry: suitable | technique(s) - | technique(s) - |
| biological source bovine milk | biological source bovine milk | biological source bovine milk | biological source - |
| form essentially salt-free, lyophilized powder | form purified powder | form lyophilized powder | form - |
| storage temp. −20°C | storage temp. - | storage temp. 2-8°C | storage temp. - |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. - |
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Faites votre choix parmi les versions les plus récentes :
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
-
What is Product C9801, N,N-dimethylated casein, soluble in?
1 réponse-
Utile ?
-
-
What is the purity of Product No. C9801, N,N-dimethylated casein?
1 réponse-
This product is not sold by purity, but by the percent of N,N-methylation. It is required to be at least 90% methylated.
Utile ?
-
-
What is the molecular weight of Product C9801, N,N-dimethylated casein?
1 réponse-
Unfortunately, we have not determined the molecular weight. The molecular weight of casein is 26 kDa or less; the molecular weight of Product No. C9801 is expected to be a bit higher.
Utile ?
-
-
What is the Department of Transportation shipping information for this product?
1 réponse-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
Utile ?
-
-
How does the storage temperature relate to shipping conditions?
1 réponse-
The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.
Utile ?
-