This product is soluble in water at 50 mg/mL. The storage and stability conditions for this product upon reconstitution have not been determined.
C7527
Chlorure de choline
BioReagent, suitable for cell culture, suitable for insect cell culture, ≥98%
Synonyme(s) :
Chlorure de (2-hydroxyéthyl)triméthylammonium
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100 G
59,60 €
500 G
173,00 €
1 KG
270,00 €
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Changer de vue
100 G
59,60 €
500 G
173,00 €
1 KG
270,00 €
About This Item
Formule linéaire :
(CH3)3N(Cl)CH2CH2OH
Numéro CAS:
Poids moléculaire :
139.62
Beilstein:
3563126
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352205
ID de substance PubChem :
Nomenclature NACRES :
NA.75
Source biologique
synthetic (organic)
Gamme de produits
BioReagent
Essai
≥98%
Forme
crystals
Poids mol.
Mw 139.62 g/mol
Technique(s)
cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable
Couleur
white
pH
5.0-6.5 (25 °C, 140 g/L)
Pf
302-305 °C (dec.) (lit.)
Solubilité
H2O: 50 mg/mL
Chaîne SMILES
[Cl-].C[N+](C)(C)CCO
InChI
1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
Clé InChI
SGMZJAMFUVOLNK-UHFFFAOYSA-M
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Description générale
Application
Choline chloride has been used:
- as a component of choline acetyltransferase (ChAT) buffer and for choline uptake in cultured human neuroblastoma (SK-N-SH) cells[3]
- for choline standard curve generation for quantifying phospholipase D (PLD) activity[4]
- as a component of slice solution for the dissection of entorhinal-hippocampal brain slices[5]
Substrats
Substrat de la choline acétyltransférase
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
dust mask type N95 (US), Eyeshields, Gloves
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Harvie P Portugaliza et al.
Scientific reports, 9(1), 14595-14595 (2019-10-12)
Transmission of malaria parasites from humans to mosquito vectors requires that some asexual parasites differentiate into sexual forms termed gametocytes. The balance between proliferation in the same host and conversion into transmission forms can be altered by the conditions of
Choline: an essential nutrient for public health
Zeisel SH and Da Costa KA
Nutr. Rev, 67(11), 615-623 (2009)
Synthesis and characterization of choline chloride based binary mixtures
Abbas Q and Binder L
ECS Transactions, 33(7), 49-59 (2010)
Apoptosis of bovine granulosa cells: Intracellular pathways and differentiation
Carou MC, et al.
Acta Histochemica, 119(5), 462-470 (2017)
Zhenglin Gu et al.
Cell reports, 31(10), 107740-107740 (2020-06-11)
Muscarinic acetylcholine receptors (mAChRs) are critically involved in hippocampal theta generation, but much less is known about the role of nicotinic AChRs (nAChRs). Here we provide evidence that α7 nAChRs expressed on interneurons, particularly those in oriens lacunosum moleculare (OLM)
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Choline chloride will be melted in water for addition to the medium. Can you please tell me the proper storage method, such as -30°C freezing ay -4°C refrigeration?
1 réponse-
Utile ?
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Hi, is it possible to thaw choline chloride in PBS instead of water and add it to the medium?
1 réponse-
This product is soluble in water, tested at 50 mg/mL. Solubility in PBS has not been determined in-house. Literature suggests that choline chloride can be prepared with PBS. For reference, see https://en-cdn.bio-protocol.org/pdf/Bio-protocol807.pdf?rel_link=YmlvLXByb3RvY29sLm9yZy9lbi9icGRldGFpbD9pZD04MDcmdHlwZT0w
Utile ?
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Hi, could you please provide the product information sheet for Choline chloride.
1 réponse-
There is no specific product information sheet offered for Choline Chloride. Please see the PROPERTIES section of the product page for details. Links to a sample Certificate of Analysis and a Certificate of Origin are provided below:
Certificate of Analysis
https://www.sigmaaldrich.com/certificates/COFA/C7/C7527/C7527-100G________SLBB8921V_.pdfCertificate of Origin
https://www.sigmaaldrich.com/US/en/coo/undefined/C7527/SLBB8921VUtile ?
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