Product C5874 (Cidofovir hydrate) is soluble at 22 mg/mL in water, with warming for 3-5 minutes in a 60°C heat bath.
C5874
Cidofovir hydrate
≥98% (HPLC), powder, viral DNA synthesis inhibitor
Synonyme(s) :
(S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine, (S)-HPMPC; Cidovir, HPMPC, Vistide
Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Sélectionner une taille de conditionnement
10 MG
87,50 €
50 MG
314,00 €
Sélectionner une taille de conditionnement
Changer de vue
10 MG
87,50 €
50 MG
314,00 €
About This Item
Formule empirique (notation de Hill) :
C8H14N3O6P · xH2O
Numéro CAS:
Poids moléculaire :
279.19 (anhydrous basis)
Numéro MDL:
Code UNSPSC :
12352200
ID de substance PubChem :
Nomenclature NACRES :
NA.77
Nom du produit
Cidofovir hydrate, ≥98% (HPLC)
Essai
≥98% (HPLC)
Forme
powder
Conditions de stockage
desiccated
protect from light
Solubilité
deionized water: ≥5 mg/mL (warmed)
Température de stockage
room temp
Chaîne SMILES
O.NC1=NC(=O)N(C[C@@H](CO)OCP(O)(O)=O)C=C1
InChI
1S/C8H14N3O6P.H2O/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16;/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16);1H2/t6-;/m0./s1
Clé InChI
KLJYJZIIJLYJNN-RGMNGODLSA-N
Vous recherchez des produits similaires ? Visite Guide de comparaison des produits
Actions biochimiques/physiologiques
Selective inhibitor of viral DNA synthesis through the selective inhibition of viral DNA polymerase.
Caractéristiques et avantages
This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Mention d'avertissement
Danger
Mentions de danger
Conseils de prudence
Classification des risques
Acute Tox. 3 Oral - Skin Irrit. 2
Code de la classe de stockage
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Faites votre choix parmi les versions les plus récentes :
Certificats d'analyse (COA)
Lot/Batch Number
Vous ne trouvez pas la bonne version ?
Si vous avez besoin d'une version particulière, vous pouvez rechercher un certificat spécifique par le numéro de lot.
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Michel Bossens et al.
International journal of clinical pharmacology and therapeutics, 56(3), 134-141 (2018-01-11)
The primary objective was to evaluate the safety and local tolerance of a topical 2% (w/w) cidofovir gel, applied directly to the cervices of women with high-grade cervical intraepithelial neoplasia (CIN 2+). The secondary objective was to evaluate the pharmacokinetics
Stephen D S McCarthy et al.
PLoS neglected tropical diseases, 10(1), e0004364-e0004364 (2016-01-12)
To date there are no approved antiviral drugs for the treatment of Ebola virus disease (EVD). While a number of candidate drugs have shown limited efficacy in vitro and/or in non-human primate studies, differences in experimental methodologies make it difficult
Erika Trompet et al.
Antiviral research, 182, 104901-104901 (2020-08-09)
Murine γ-herpesvirus-68 (MHV-68), genetically and biologically related to human γ-herpesviruses Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus, can be easily propagated in vitro allowing drug resistance studies. Previously, we described specific changes in MHV-68 protein kinase (PK) or thymidine kinase (TK)
Joanna Jackowska et al.
Lasers in medical science, 34(7), 1433-1440 (2019-02-15)
Mechanical debulking of laryngeal papillomas is associated with voice disorders due to impairment of the vocal fold's mucosa. Intraepithelial injection of cidofovir reduces damage to the laryngeal structures and thus improves vocal parameters. The aim of our study was to
Successful treatment of perianal giant condyloma acuminatum in an immunocompromised host with systemic interleukin 2 and topical cidofovir.
Vinod E Nambudiri et al.
JAMA dermatology, 149(9), 1068-1070 (2013-07-05)
Articles
Bioactive small molecules for immune system signaling target identification/validation and antibiotics, antivirals, and antifungals offered.
Discover Bioactive Small Molecules for ADME/Tox
-
What is the solubility of Product C5874 (Cidofovir hydrate)?
1 réponse-
Utile ?
-
-
What is the Department of Transportation shipping information for this product?
1 réponse-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
Utile ?
-
Filtres actifs
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
Contacter notre Service technique
