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C1671

Chlorprothixene hydrochloride

Synonyme(s) :

2-Chloro-9-(3-dimethylaminopropylidene)thioxanthene hydrochloride

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A propos de cet article

Formule empirique (notation de Hill) :
C18H18ClNS · HCl
Numéro CAS:
6469-93-8
Poids moléculaire :
352.32
NACRES:
NA.77
PubChem Substance ID:
24278300
UNSPSC Code:
12352200
EC Number:
229-289-3
MDL number:
MFCD01941605
Form:
powder

form

powder

storage temp.

2-8°C

SMILES string

Cl.CN(C)CC\C=C1\c2ccccc2Sc3ccc(Cl)cc13

InChI

1S/C18H18ClNS.ClH/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18;/h3-4,6-10,12H,5,11H2,1-2H3;1H/b14-7-;

InChI key

YWKRLOSRDGPEJR-KIUKIJHYSA-N

Gene Information

human ... DRD2(1813), DRD3(1814), HTR2A(3356), HTR2C(3358)

General description

Chlorprothixene is a neuroleptic drug, which belongs to thioxanthene group. It has anticholinergic effects. Chlorprothixene might be associated with obstructive jaundice and parkinsonism. It is used to treat psychosis.

Application

Chlorprothixene hydrochloride has been used to study its exposure effects on learning and memory of rats.

Biochem/physiol Actions

D2 dopamine receptor antagonist; blocks a subset of GABAA receptors in rat cortex that is also blocked by clozapine; thioxanthine antipsychotic.

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Cet article
C1915000P4670E5406
Chlorprothixene hydrochloride

Sigma-Aldrich

C1671

Chlorprothixene hydrochloride

Chlorprothixene hydrochloride European Pharmacopoeia (EP) Reference Standard

C1915000

Chlorprothixene hydrochloride

Propafenone hydrochloride

Sigma-Aldrich

P4670

Propafenone hydrochloride

Ethopropazine hydrochloride ≥98% (HPLC), powder

Sigma-Aldrich

E5406

Ethopropazine hydrochloride

form

powder

form

-

form

powder

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Gene Information

human ... DRD2(1813), DRD3(1814), HTR2A(3356), HTR2C(3358)

Gene Information

human ... DRD2(1813), DRD3(1814), HTR2A(3356), HTR2C(3358)

Gene Information

human ... ABCB1(5243), ADRB1(153), ADRB2(154), ADRB3(155), CYP1A2(1544), SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Gene Information

human ... CHRM1(1128)

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pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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