If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
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For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
A4665
Alaméthicine from Trichoderma viride
≥98% (HPLC)
Synonyme(s) :
Antibiotique U-22324
Sélectionner une taille de conditionnement
| À vous/Référence | Disponibilité | Prix |
|---|---|---|
5 mg | Vérifier la disponibilité des articles du panier | 522,00 € |
10 mg | Vérifier la disponibilité des articles du panier | 911,00 € |
25 mg | Vérifier la disponibilité des articles du panier | 1 900,00 € |
A propos de cet article
Quality Segment
assay
≥98% (HPLC)
form
powder
antibiotic activity spectrum
Gram-positive bacteria
mode of action
cell membrane | interferes
storage temp.
2-8°C
SMILES string
CC(C)C[C@H](NC(=O)CNC(=O)C(C)(C)NC(=O)[C@@H](NC(=O)C(C)(C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)C(C)(C)NC(=O)[C@H](C)NC(=O)C(C)(C)NC(=O)[C@@H]1CCCN1C(=O)C(C)(C)NC(C)=O)C(C)C)C(=O)NC(C)(C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](C(C)C)C(=O)NC(C)(C)C(=O)NC(C)(C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)Cc3ccccc3
InChI
1S/C92H150N22O25/c1-47(2)43-58(72(127)108-92(24,25)84(139)113-41-29-33-59(113)73(128)103-65(48(3)4)75(130)111-90(20,21)82(137)112-89(18,19)80(135)102-56(37-40-64(120)121)70(125)101-55(35-38-61(93)117)69(124)98-54(46-115)44-53-31-27-26-28-32-53)99-63(119)45-95-77(132)85(10,11)110-76(131)66(49(5)6)104-81(136)88(16,17)107-71(126)57(36-39-62(94)118)100-67(122)50(7)96-78(133)86(12,13)106-68(123)51(8)97-79(134)87(14,15)109-74(129)60-34-30-42-114(60)83(138)91(22,23)105-52(9)116/h26-28,31-32,47-51,54-60,65-66,115H,29-30,33-46H2,1-25H3,(H2,93,117)(H2,94,118)(H,95,132)(H,96,133)(H,97,134)(H,98,124)(H,99,119)(H,100,122)(H,101,125)(H,102,135)(H,103,128)(H,104,136)(H,105,116)(H,106,123)(H,107,126)(H,108,127)(H,109,129)(H,110,131)(H,111,130)(H,112,137)(H,120,121)/t50-,51-,54+,55-,56-,57-,58-,59-,60-,65-,66-/m0/s1
InChI key
LGHSQOCGTJHDIL-SLKIUSOBSA-N
General description
Application
- les effets des transporteurs du glutamate sur l'élévation transitoire de la concentration en K+ extracellulaire dépendante de l'ATPase Na+/K+ au cours de l'activité neuronale[3]
- la formation de canaux perméables aux anions, dans des bicouches lipidiques planes, par de la magainine I obtenue à partir de peau de Xenopus[1]
- la perméabilité de l'épiderme et du méristème apical des racines et la résistance à l'alaméthicine induite par la cellulase chez Arabidopsis thaliana[2]
- les effets cytotoxiques de l'acide okadaïque (phycotoxine) et des mycotoxines sur des lignées de cellules intestinales humaines (HT-29) et de cellules de neuroblastome (SH-SY5Y)[4]
- les variations de structure et l'activité biologique de peptaïbols obtenus à partir du clade Longibrachiatum appartenant au genre de champignons filamenteux Trichoderma[5]
Biochem/physiol Actions
Analysis Note
Other Notes
1 of 1
Cet article | |||
|---|---|---|---|
| antibiotic activity spectrum Gram-positive bacteria | antibiotic activity spectrum Gram-positive bacteria | antibiotic activity spectrum fungi, yeast | antibiotic activity spectrum fungi, yeast |
| mode of action cell membrane | interferes | mode of action cell membrane | interferes | mode of action cell membrane | interferes | mode of action cell membrane | interferes |
| Quality Level 300 | Quality Level 200 | Quality Level 300 | Quality Level 300 |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ~80% (HPLC) | assay ~80% (HPLC) |
| form powder | form DMSO solution | form powder | form solid |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
Classe de stockage
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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