262A-1

Granzyme B Rabbit Polyclonal Antibody

• NACRES: NA.41
• UNSPSC Code: 12352203
• Conjugate: unconjugated
• Clone: polyclonal
• Application: IHC (p)
• Citations: 5

Propriétés

• biological source: rabbit
• Quality Segment: 100, 500
• conjugate: unconjugated
• antibody form: Ig fraction of antiserum
• antibody product type: primary antibodies
• clone: polyclonal
• description: For In Vitro Diagnostic Use in Select Regions (See Chart)
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL concentrate (262A-14), vial of 0.5 mL concentrate (262A-15), bottle of 1.0 mL predilute (262A-17), vial of 1.0 mL concentrate (262A-16), bottle of 7.0 mL predilute (262A-18)
• manufacturer/tradename: Cell Marque^®
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:10-1:50
• control: ALCL, spleen
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: cytoplasmic
• Gene Information: human ... GZMB(3002)

Description

General description

Granzymes are serine proteases which are stored in specialized lytic granules of cytotoxic T-lymphocytes and in natural killer cells.[1] Anti-granzyme B has been useful in diagnosing natural killer/T-cell lymphoma, as well as anaplastic large cell lymphoma. High percentages of cytotoxic T-cells have been shown to be an unfavorable indicator in Hodgkin disease.[2][3][4][5]

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note

IVD

IVD

IVD

RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: [email protected]

Granzyme B Positive Control Slides, Product No. 262S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany