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Merck
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24370C

SAFC

EX-CELL® Advanced HD Perfusion Medium

powder

Fabrication pharma

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About This Item

Code UNSPSC :
12352200

Niveau de qualité

500

Gamme de produits

EX-CELL®

Forme

dry powder

Technique(s)

cell culture | mammalian: suitable (suspension)

Conditions d'expédition

ambient

Température de stockage

2-8°C

Description générale

EX-CELL® Advanced HD Perfusion Medium is chemically-defined and contains no animal derived components. The new medium has been specifically developed to support growth and productivity across a diverse set of Chinese Hamster Ovary (CHO) cells in perfusion cultures while still allowing for flexibility in the adjustment of protein quality attributes. This medium was developed using a strategy of Multivariate Analysis to establish correlations in which the formulation components influence critical process and product attributes such as titer, fold expansion, protein expression and glycosylation. This medium is intended to be used in perfusion processes. While the medium was developed specifically for steady-state perfusion, it can also support other perfusion applications such as N-1, continuous fed-batch and production perfusion where cells are not bled.

Quantité

Formulated to contain 28.57 grams of powder per liter of medium.

Informations légales

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H315,H319

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Certificats d'analyse (COA)

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Articles

Establishing the First GMP Guideline for Cell Culture Media

Cell culture media are vital for bioprocessing therapeutics. This page describes the central role of our organization in authoring purpose-built GMP for cell culture media.

CHO Media and Feeds for Optimized Production of Therapeutic Proteins

Cellvento® and EX-CELL® CHO cell culture media and feeds, optimized for monoclonal antibody & recombinant protein production in fed-batch & perfusion

Contenu apparenté

Production and Harvest Intensification

Biopharmaceutical developers need efficient, productive upstream processes that deliver high quality monoclonal antibodies (mAbs) and other types of recombinant proteins. Process intensification can future-proof their manufacturing strategies, reduce costs, and increase facility flexibility.

Intensification de la production et de la récolte

Les développeurs biopharmaceutiques ont besoin de procédés upstream qui soient efficaces et productifs afin de produire des anticorps monoclonaux (mAbs) et d'autres types de protéines recombinantes de haute qualité. L'intensification des procédés permet d'assurer la pérennité de leurs stratégies de fabrication, de réduire les coûts et d'accroître la polyvalence de leurs installations.

Amplify Your Upstream Ecosystem

Eliminate the need to clean, autoclave and assemble your traditional glass bioreactors and save days of downtime with the Mobius® 3L Single-use Bioreactor.

Accelerate development and optimization of cell culture media for upstream perfusion processes

This page describes the use of a small-scale perfusion bioreactor with integrated microfluidic flow control and sensor technologies to predict large-scale processes.

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