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PHR1046

Supelco

Éthylène glycol

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

1,2-Éthanediol

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1 G
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About This Item

Formule linéaire :
HOCH2CH2OH
Numéro CAS:
107-21-1
Poids moléculaire :
62.07
Beilstein:
505945
Numéro CE :
203-473-3
Numéro MDL:
MFCD00002885
Code UNSPSC :
41116107
eCl@ss :
39020501
ID de substance PubChem :
329823076
Nomenclature NACRES :
NA.24

75,80 €

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Devis pour commande en gros

Qualité

certified reference material
pharmaceutical secondary standard

Niveau de qualité

300

Agence

traceable to USP 1265515

Densité de vapeur

2.1 (vs air)

Pression de vapeur

0.08 mmHg ( 20 °C)

CofA (certificat d'analyse)

current certificate can be downloaded

Température d'inflammation spontanée

752 °F

Limite d'explosivité

15.3 %

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Indice de réfraction

n20/D 1.431 (lit.)

pb

195-198 °C

Pf

−13 °C (lit.)

Densité

1.113 g/mL at 25 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-30°C

Chaîne SMILES 

OCCO

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

Clé InChI

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Description générale

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ethylene glycol can also be produced from fossil fuels (petroleum, natural gas and coal) and biomass-derived resources. It is a polyol having a wide range of industrial applications.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. Ethylene glycol may be used as a standard in the determination of ethylene glycol present in serum samples using gas chromatography (GC).[1]

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Autres remarques

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAC2089 in the slot below. This is an example certificate only and may not be the lot that you receive.

Produits recommandés

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictogrammes

Health hazardExclamation mark
GHS08,GHS07

Mention d'avertissement

Warning

Mentions de danger

H302,H373

Classification des risques

Acute Tox. 4 Oral - STOT RE 2 Oral

Organes cibles

Kidney

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

239.0 °F - open cup

Point d'éclair (°C)

115 °C - open cup

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Gas-chromatographic determination of ethylene glycol in serum
Porter H.W and Auansakul aA
Clinical Chemistry, 28, 75-78 (1982)
Peter Mygind Leth et al.
Forensic science international, 155(2-3), 179-184 (2005-10-18)
Ethylene glycol (EG) can be found in many agents, such as antifreeze. Ingestion of EG may cause serious poisoning. Adults are typically exposed when EG is ingested as a cheap substitute for ethanol or in suicide-attempts. Children may be exposed
Yi Wang et al.
Journal of the American Chemical Society, 135(5), 1941-1951 (2013-01-16)
This article describes a robust method for the facile synthesis of small Ag nanocubes with edge lengths controlled in the range of 18-32 nm. The success of this new method relies on the substitution of ethylene glycol (EG)--the solvent most
Mona Sheikhi et al.
Fertility and sterility, 100(1), 170-177 (2013-04-10)
To study the preservation of follicles within ovarian tissue vitrified using only one or a combination of three permeating cryoprotectants. Experimental study. University hospital. Ovarian tissue was donated by consenting women undergoing elective cesarean section. Ovarian tissue was vitrified in
Andrea Marchionni et al.
ChemSusChem, 6(3), 518-528 (2013-02-14)
The electrooxidation of ethylene glycol (EG) and glycerol (G) has been studied: in alkaline media, in passive as well as active direct ethylene glycol fuel cells (DEGFCs), and in direct glycerol fuel cells (DGFCs) containing Pd-(Ni-Zn)/C as an anode electrocatalyst
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Chromatograms

suitable for GC

Questions

1–4 sur 4 questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 réponse

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 réponse

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. What is the Department of Transportation shipping information for this product?

    1 réponse

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  4. What is the molarity of ethylene glycol?

    1 réponse

    1. Ethylene glycol is 17.93M.  This is calculated using the density (1.113 g/ml) and the molecular weight (62.07 g/mol).  If the product is less than 100% pure, correct for the purity.

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