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M2523

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Mebendazole

analytical standard, ≥98% (HPLC)

Synonyme(s) :

5-Benzoyl-2-benzimidazolecarbamic acid methyl ester, Mebendazol, Methyl N-(5-benzoyl-1H-benzimidazol-2-yl)carbamate

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About This Item

Formule empirique (notation de Hill):
C16H13N3O3
Numéro CAS:
31431-39-7
Poids moléculaire :
295.29
Numéro Beilstein :
759809
Numéro CE :
250-635-4
Numéro MDL:
MFCD00057872
Code UNSPSC :
41116107
ID de substance PubChem :
329817943
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

100

Pureté

≥98% (HPLC)

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

forensics and toxicology
pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3ccccc3

InChI

1S/C16H13N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,17,18,19,21)

Clé InChI

OPXLLQIJSORQAM-UHFFFAOYSA-N

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Catégories apparentées

Description générale

Mebendazole is a benzimidazole carbamate derivative, which is an anthelmintic agent.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
WXBF2283V
WXBD9122V
MKCP7442
MKCK9648
MKCJ1313

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The Antimicrobial Drugs (2000)
Sara Carlert et al.
Molecular pharmaceutics, 9(10), 2903-2911 (2012-09-08)
The purpose of this study was to investigate in vivo intestinal precipitation of a model drug mebendazole, a basic BCS class II drug, using dogs with intestinal stomas for administration or sampling. After oral administration of a solution with an
Peter Nygren et al.
Journal of cancer research and clinical oncology, 139(12), 2133-2140 (2013-10-19)
In the present study, we screened a compound library containing 1,600 clinically used compounds with the aim to identify compounds, which potentially could be repositioned for colon cancer therapy. Two established colon cancer cell lines were tested using the fluorometric
Sivanesan Dakshanamurthy et al.
Journal of medicinal chemistry, 55(15), 6832-6848 (2012-07-12)
The most effective way to move from target identification to the clinic is to identify already approved drugs with the potential for activating or inhibiting unintended targets (repurposing or repositioning). This is usually achieved by high throughput chemical screening, transcriptome
Monica Longo et al.
Reproductive toxicology (Elmsford, N.Y.), 36, 78-87 (2013-01-05)
Filarial diseases affect millions of people in poverty-stricken areas. In 2011, an investigation of the potential of flubendazole as a safe, highly efficacious, and field-usable macrofilaricidal drug was begun by Drug for Neglected Diseases initiative. As part of the preclinical
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