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G2164

Sigma-Aldrich

Gluconolactone

99.0-101.0%, meets USP testing specifications

Synonyme(s) :

D-(+)-Gluconic acid δ-lactone, δ-Gluconolactone, 1,2,3,4,5-Pentahydroxycaproic acid δ-lactone, D-(+)-Dextronic acid δ-lactone

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About This Item

Formule empirique (notation de Hill):
C6H10O6
Numéro CAS:
Poids moléculaire :
178.14
Numéro Beilstein :
83286
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352201
ID de substance PubChem :
Nomenclature NACRES :
NA.21

Source biologique

corn

Niveau de qualité

Agence

USP/NF
meets USP testing specifications

Pureté

99.0-101.0%

Forme

crystalline

Couleur

white

Pf

160 °C (dec.) (lit.)

Solubilité

water: soluble

Application(s)

pharmaceutical (small molecule)

Chaîne SMILES 

OC[C@H]1OC(=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H10O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-5,7-10H,1H2/t2-,3-,4+,5-/m1/s1

Clé InChI

PHOQVHQSTUBQQK-SQOUGZDYSA-N

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Description générale

Gluconolactone is a non-toxic component of the skin. It has anti-oxidant and free radical scavenging effects. Gluconolactone has antiaging and skin-firming properties. It acts as a β-glucosidase inhibitor. Gluconolactone stimulates cellulase gene expression.

Application

Gluconolactone has been used:
  • to control the acidification kinetics of natural rubber latex (NRL) suspensions
  • to study its effects on inhibition and disintegration of collagen fibrils
  • to prepare alginate hydrogel

Actions biochimiques/physiologiques

Glucono-d-lactone increased the doubling time and activated enzymes involved in the oxidative pentose phosphate pathway of Saccharomyces cerevisiae.

Autres remarques

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Consulter la Bibliothèque de documents

Procedures in Cosmetic Dermatology Series: Cosmeceuticals E-Book (2008)
Acid-induced aggregation and gelation of natural rubber latex particles
de Oliveira Reis G, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 482(68), 9-17 (2015)
Guilherme de Oliveira Reis et al.
Journal of colloid and interface science, 539, 287-296 (2018-12-28)
Natural rubber is obtained by processing natural rubber latex, a liquid colloidal suspension that rapidly gels after exudation from the tree. We prepared such gels by acidification, in a large range of particle volume fractions, and investigated their rheological properties.
Gluconolactone induces cellulase gene expression in cellulolytic filamentous fungus Trichoderma reesei
Kou Y, et al.
Royal Society of Chemistry Advances, 4(68), 36057-36063 (2014)
Elizabeth W Ng et al.
International journal of food microbiology, 145(1), 169-175 (2011-01-05)
Recognized to confer health benefits to consumers, probiotics such as Lactobacillus acidophilus are commonly incorporated into fermented dairy products worldwide; among which yogurt is a popular delivery vehicle. To materialize most of the putative health benefits associated with probiotics, an

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