This purity of this product is not determined.
F6377
Fluorescein sodium salt
Fluorescein sodium salt
Powder
Synonyme(s) :
Acid Yellow 73, D&C;Yellow No. 8, NaFl, NaFluo, Sodium fluorescein, Uranine
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About This Item
Formule empirique (notation de Hill):
C20H10Na2O5
Numéro CAS:
Poids moléculaire :
376.27
Numéro C.I. (Colour Index):
45350
Beilstein:
3833041
Numéro CE :
Numéro MDL:
Code UNSPSC :
12171500
ID de substance PubChem :
Nomenclature NACRES :
NA.47
Le tarif et la disponibilité ne sont pas disponibles actuellement.
Produits recommandés
Nom du produit
Fluorescein sodium salt, used as fluorescent tracer
Niveau de qualité
Forme
powder
Technique(s)
titration: suitable
Couleur
orange to brown
pH
8.3 (20 °C, 10 g/L)
Pf
>300 °C
Solubilité
H2O: 1 mg/mL
Densité
0.78 g/cm3 at 29.6 °C (85.3 °F at 699.7 hPa)
Fluorescence
λex 460 nm; λem 515 nm(lit.)
Application(s)
diagnostic assay manufacturing
hematology
histology
Température de stockage
room temp
Chaîne SMILES
[Na+].[Na+].[O-]c1ccc2c(Oc3cc([O-])ccc3C24OC(=O)c5ccccc45)c1
InChI
1S/C20H12O5.2Na/c21-11-5-7-15-17(9-11)24-18-10-12(22)6-8-16(18)20(15)14-4-2-1-3-13(14)19(23)25-20;;/h1-10,21-22H;;/q;2*+1/p-2
Clé InChI
RGPLGPBQJOQFJS-UHFFFAOYSA-L
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Description générale
Fluorescein is a xanthene dye and is a common labeling agent in biology.[1]
Application
Fluorescein sodium salt has been used as a solute to study microvessel permeability.[2][3] It has been used as a test molecule to study blood barrier penetration.[4]
Water soluble fluorescent dye used in permeability and vascular perfusion studies due to its small molecular radius.[5] Sodium fluorescein is used as a fluorescent tracer to study blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB) permeability in rodent models.[6][7][8] The dye was used as a probe substrate in the study of organic anion transporting polypeptide (OATP) mediated drug transport in hepatocytes.[9] Sodium fluorescein was also used to monitor in situ solute transportation into bone through fluorescence recovery after photobleaching (FRAP).[10]
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
423.7 °F - Pensky-Martens closed cup
Point d'éclair (°C)
217.6 °C - Pensky-Martens closed cup
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
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Certificats d'analyse (COA)
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Les clients ont également consulté
P Kozler et al.
Physiological research, 52(5), 607-614 (2003-10-11)
The aim was to study the blood-brain permeability according to the distribution in the rat brain of Evans blue (EB) and sodium fluorescein (NaFl) administered by an intracarotid injection. Eighteen animals were divided into six groups according to the state
D Montermini et al.
The Journal of physiology, 543(Pt 3), 959-975 (2002-09-17)
The permeability, P(S), to sodium fluorescein (Stokes-Einstein radius = 0.45 nm) has been measured in single mesenteric capillaries of pithed frogs and anaesthetised rats as perfusion velocity, U, was varied over a range from 400 up to 2000-10,000 microm s(-1).
Temperature dependence of electronic parameters of organic Schottky diode based on fluorescein sodium salt.
Yahia IS, et al.
Synthetic Metals, 161(9), 881-887 (2011)
Dimitris N Xanthos et al.
Molecular pain, 8, 44-44 (2012-06-21)
Changes in the blood-central nervous system barriers occur under pathological conditions including inflammation and contribute to central manifestations of various diseases. After short-lasting peripheral and neurogenic inflammation, the evidence is mixed whether there are consistent blood-spinal cord changes. In the
The acute and chronic toxicity of two xanthene dyes, fluorescein sodium salt and phloxine B, to Daphnia pulex.
Walthall WK and Stark JD.
Environmental Pollution (Barking, Essex : 1987), 104(2), 207-215 (1999)
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What is the purity of Fluorescein sodium salt (CAS number 518-47-8, article number F6377-100G)?
1 réponse-
Utile ?
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Can this product be autoclaved once dissolved? How long can a concentrated dissolved stock solution be stored for?
1 réponse-
The stability of Fluorescein under autoclave conditions has not been determined. Solutions have typically been filter sterilized. Long term solution stability has also not been evaluated. However, solutions of Fluorescein Diacetate are stable at -20°C in ethanol when protected from light. Similar stability would be expected with the sodium salt form.
Utile ?
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Hello, I am interested in Fluorescein or Fluoresein sodium salt to perform angiography in the living mouse and would like to know if your product has a pharmacological grade. Which product is used for angiography?
1 réponse-
Unfortunately, a pharmacological grade Fluorescein or Fluorescein sodium salt is not available at this time.
Utile ?
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Is F6377 soluble in ethanol?
1 réponse-
The substance is soluble in water (500 g/l) at 20°C and slightly soluble in ethanol, but insoluble in benzene, chloroform, and ether.
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