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E0050000

Econazole nitrate

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

1-[2-[(4-Chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole mononitrate, 1-{2,4-Dichloro-β-[(p-chlorobenzyl)oxy}phenethyl]imidazole mononitrate

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About This Item

Formule empirique (notation de Hill):
C18H16Cl3N3O4
Numéro CAS:
68797-31-9
Poids moléculaire :
444.70
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

econazole

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

InChI

1S/C18H15Cl3N2O.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;2-1(3)4/h1-9,12,18H,10-11H2;(H,2,3,4)

Clé InChI

DDXORDQKGIZAME-UHFFFAOYSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Econazole nitrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Y0000254

Econazole for system suitability, European Pharmacopoeia (EP) Reference Standard

Y0001236

Econazole, European Pharmacopoeia (EP) Reference Standard

1231808

Econazole nitrate, United States Pharmacopeia (USP) Reference Standard

1231830

Econazole Related Compound A, United States Pharmacopeia (USP) Reference Standard

1231841

Econazole Related Compound B, United States Pharmacopeia (USP) Reference Standard

1231852

Econazole Related Compound C, United States Pharmacopeia (USP) Reference Standard

PHR2232

Econazole Impurity D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2231

Econazole Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302,H315,H319

Classification des risques

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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To design a contact lens to treat and prevent fungal ocular infections. Curved contact lenses were created by encapsulating econazole-impregnated poly(lactic-co-glycolic) acid (PLGA) films in poly(hydroxyethyl methacrylate) (pHEMA) by ultraviolet photopolymerization. Release studies were conducted in phosphate-buffered saline at 37°C
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Biopolymers, 97(4), 219-228 (2011-11-25)
The binding free energies of the inhibitor-heme model complexes are calculated using the density functional methods and the implicit solvation models in water, where the 16 structurally diverse compounds with a spectrum of IC(50) values from 0.05 (clotrimazole) to 1000
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Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 27(3-4), 373-380 (2011-04-08)
Oleic acid is the principal fatty acid of olive oil composition and is reported to play a crucial role in its healthy aspects. However, the detailed mechanism of action is poorly understood. This study aims to elucidate the role of
Suhyun Kim et al.
Bioorganic & medicinal chemistry letters, 22(22), 6844-6847 (2012-10-13)
Econazole has been known to be active against Mycobacterium tuberculosis. We have designed and synthesized 1H-1,2,3-triazoles derived from econazole as antitubercular agents. The majority of triazole derivatives have been prepared by microwave-assisted click chemistry. It turned out that all of
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Analytical and bioanalytical chemistry, 402(3), 1241-1247 (2011-11-08)
A simple and efficient method, based on ultrasound-enhanced surfactant-assisted dispersive liquid-liquid microextraction (UESA-DLLME) followed by high-performance liquid chromatography (HPLC) has been developed for extraction and determination of ketoconazole and econazole nitrate in human blood samples. In this method, a common
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