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D7282

Supelco

Desmethyldiazepam

analytical standard

Synonyme(s) :

Nordiazepam

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About This Item

Formule empirique (notation de Hill):
C15H11ClN2O
Numéro CAS:
1088-11-5
Poids moléculaire :
270.71
Numéro CE :
214-123-4
Numéro MDL:
MFCD00063440
Code UNSPSC :
41116107
ID de substance PubChem :
329798847
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

100

Pureté

≥98% (HPLC)

Forme

powder

Contrôle du médicament

USDEA Schedule IV; Home Office Schedule 4.1; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Couleur

white to light tan

Solubilité

DMSO: >10 mg/mL

Application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Format

neat

Température de stockage

room temp

Chaîne SMILES 

Clc1ccc2NC(=O)CN=C(c3ccccc3)c2c1

InChI

1S/C15H11ClN2O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9H2,(H,18,19)

Clé InChI

AKPLHCDWDRPJGD-UHFFFAOYSA-N

Informations sur le gène

rat ... Tspo(24230)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Actions biochimiques/physiologiques

Primary metabolite of diazepam; ligand for the GABAA receptor benzodiazepine modulatory site.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
0000367913
0000365545
0000330773
0000285273
0000368099

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Pi Cheng et al.
Bioorganic & medicinal chemistry letters, 18(13), 3787-3789 (2008-06-06)
A series of 4-aryl-6-chloro-quinolin-2-ones and 5-aryl-7-chloro-1,4-benzodiazepine were synthesized and assayed for their in vitro anti-hepatitis B virus activities and cytotoxicities for the first time. Some of the tested compounds were active against HBsAg and HBeAg secretion in Hep G2.2.15 cells.
Joris C Verster et al.
Sleep medicine reviews, 17(2), 153-159 (2012-08-14)
The use of benzodiazepine receptor agonists can significantly impair driving performance. The aim of this review was to determine if there is a relation between blood concentrations of these drugs and the degree of driving impairment. A literature search was
Laura Mercolini et al.
Talanta, 80(1), 279-285 (2009-09-29)
Diazepam is frequently used as an adjuvant during antidepressant therapy. Recently, some studies have suggested that the treatment with benzodiazepines could have different efficacy in depressed patients as opposed to non-depressed ones. To clarify the matter, a study is currently
Michael J Lamson et al.
Clinical drug investigation, 31(8), 585-597 (2011-07-05)
Acute repetitive seizures (ARS) are a debilitating part of episodic seizure activity that can sometimes progress to status epilepticus. Currently approved treatment that can be administered by non-medical personnel to patients with ARS is a diazepam rectal gel. While effective
David A Fishbain et al.
Pain medicine (Malden, Mass.), 10(3), 565-572 (2008-11-11)
The objectives of this medicolegal case report are the following: 1) to present details of a chronic pain patient (CPP) who was placed on chronic opioid analgesic therapy (COAT), and subsequently overdosed on multiple drugs, some of which were not
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