C8731

Pantothénate de calcium

meets USP testing specifications, monograph mol wt. 476.53 (C₁₈H₃₂CaN₂O₁₀)

• Synonyme(s) : Acide D-pantothénique hemicalcium salt, (R)-(+)-N-(2,4-Dihydroxy-3,3-diméthyl-1-oxobutyl)-β-alanine hemicalcium salt, Vitamine B₅
• Formule linéaire : HOCH₂C(CH₃)₂CH(OH)CONHCH₂CH₂CO₂ ·1/2Ca
• Numéro CAS: 137-08-6
• Poids moléculaire : 238.27
• Beilstein: 3769272
• Numéro CE : 205-278-9
• Numéro MDL: MFCD00002766
• Code UNSPSC : 12352205
• eCl@ss : 34058012
• ID de substance PubChem : 24893098
• Nomenclature NACRES : NA.21

Propriétés

• Source biologique: synthetic (organic)
• Niveau de qualité: 200
• Agence: USP/NF; meets USP testing specifications
• Forme: crystalline; powder
• Poids mol.: monograph mol wt. 476.53 (C₁₈H₃₂CaN₂O₁₀)
• Technique(s): cell culture | mammalian: suitable; cell culture | plant: suitable
• Couleur: white
• Application(s): pharmaceutical (small molecule)
• Température de stockage: 2-8°C
• Chaîne SMILES: CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)O[Ca]OC(=O)CCNC(=O)[C@H](O)C(C)(C)CO
• InChI: 1S/2C9H17NO5.Ca/c2*1-9(2,5-11)7(14)8(15)10-4-3-6(12)13;/h2*7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13);/q;;+2/p-2/t2*7-;/m00./s1
• Clé InChI: FAPWYRCQGJNNSJ-UBKPKTQASA-L

Description

Description générale

Vitamin B5 or pantothenic acid is a viscous oil that is soluble in ethanol and water.[1] It is produced by plants and microorganisms.[2] d-(+)pantothenic acid is the naturally occurring form of pantothenic acid and is biologically active.[3]

Application

Précurseur dans la biosynthèse du coenzyme A.

Calcium pantothenate has been used:

• as a component of vitamin solution for synthetic media[4]
• as a component of vitamin mix for the ICS medium mix[5]
• as a component of a chemically defined diet for metal depletion studies in Drosophila[6]
• as a supplement to study coenzyme A metabolism in mouse models of non-alcoholic steatohepatitis[7]

Actions biochimiques/physiologiques

The calcium salts of panthenol are commonly used for pharmaceutical preparations.[1] Pantothenate is a component of coenzyme A[8] and is useful in its synthesis. Pantothenic acid is also involved in the synthesis of heme, cholesterol and fatty acids.[9] Since vitamin B5 is found in all foods, its deficiency is not commonly observed.[1]

Propriétés physiques

En raison du caractère instable, hygroscopique, de l′acide libre, on utilise le sel de calcium.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)