BP715

Cocaine hydrochloride

British Pharmacopoeia (BP) Reference Standard

• Synonyme(s) : Ecgonine methyl ester benzoate hydrochloride
• Formule empirique (notation de Hill): C₁₇H₂₁NO₄ · HCl
• Numéro CAS: 53-21-4
• Poids moléculaire : 339.81
• Numéro MDL: MFCD00058119
• Code UNSPSC : 41116107
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: pharmaceutical primary standard
• Famille d'API: cocaine
• Forme: solid
• Durée de conservation: limited shelf life, expiry date on the label
• Fabricant/nom de marque: BP
• drug control: estupefaciente (Spain); Decreto Lei 15/93: Tabela IB (Portugal)
• Application(s): pharmaceutical; pharmaceutical (small molecule); pharmaceutical small molecule
• Format: neat
• Température de stockage: 2-8°C
• Chaîne SMILES: Cl.COC(=O)[C@H]1[C@H](C[C@@H]2CC[C@H]1N2C)OC(=O)c3ccccc3
• InChI: 1S/C17H21NO4.ClH/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11;/h3-7,12-15H,8-10H2,1-2H3;1H/t12-,13+,14-,15+;/m0./s1
• Clé InChI: PIQVDUKEQYOJNR-VZXSFKIWSA-N

Description

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Cocaine hydrochloride BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Adrenaline and Cocaine Intranasal Solution / Epinephrine and Cocaine Intranasal Solution

Cocaine Paste

Cocaine Eye Drops

Actions biochimiques/physiologiques

Inhibits the dopamine, norepinephrine, and serotonin transporters with K_is of about 300 nM, 900 nM, and 400 nM, respectively. Unlike amphetamines, it has no effect on catecholamine release.

Conditionnement

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Autres remarques

Sales restrictions may apply.

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H300 + H330,H336,H361d
• Conseils de prudence: P202 - P260 - P264 - P271 - P280 - P304 + P340 + P310
• Classification des risques: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Repr. 2 - STOT SE 3
• Organes cibles: Central nervous system
• Code de la classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable