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Merck
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B5899

Supelco

Buflomedil hydrochloride

analytical standard

Synonyme(s) :

4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone

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About This Item

Formule empirique (notation de Hill):
C17H25NO4 · HCl
Numéro CAS:
35543-24-9
Poids moléculaire :
343.85
Numéro CE :
252-611-9
Numéro MDL:
MFCD00078965
Code UNSPSC :
41116107
ID de substance PubChem :
329773268
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

200

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Format

neat

Chaîne SMILES 

Cl.COc1cc(OC)c(C(=O)CCCN2CCCC2)c(OC)c1

InChI

1S/C17H25NO4.ClH/c1-20-13-11-15(21-2)17(16(12-13)22-3)14(19)7-6-10-18-8-4-5-9-18;/h11-12H,4-10H2,1-3H3;1H

Clé InChI

ZDPACSAHMZADFZ-UHFFFAOYSA-N

Informations sur le gène

human ... EBP(10682)

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Description générale

Buflomedil hydrochloride is a vasoactive agent. Its mode of action involves increasing the peripheral and cerebral blood flow in ischaemic tissues of patients, who are mostly affected with vascular diseases.

Application

Buflomedil hydrochloride may be used as an analytical standard for the determination of buflomedil in biological matrices using high-performance liquid chromatography technique. It may also be used as an analytical reference standard for the quantification of the analyte in pharmaceutical formulations and serum samples using electroanalytical and chromatographic techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
038F09711
038F0971

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Danik Arana Navarte et al.
Medical problems of performing artists, 26(2), 79-83 (2011-06-23)
Determine the safety and tolerance of mesotherapy as a technique for the treatment of musculoskeletal complaints in musicians. 67 patients (55.2% women) were subjected to a total of 267 mesotherapy sessions. A mesotherapy needle or normal needle was used randomly.
Paul P Dobesh et al.
Pharmacotherapy, 29(5), 526-553 (2009-04-29)
Peripheral artery disease, defined as atherosclerosis in the lower extremities, affects nearly 8.5 million people in the United States. Due to the frequent asymptomatic manifestation of peripheral artery disease, diagnosis may be delayed and its true incidence underestimated. However, some
Buflomedil: still too many fatal cardiac and neurological events.
Prescrire international, 20(115), 99-99 (2011-06-09)
Quantification of the Vasoactive Agent Buflomedil HCl in Pharmaceutical Formulation and Human Serum by Stripping Voltammetry and Liquid Chromatography
El-Desoky.SH, et al.
Acta Chimica Slovenica, 57(2), 18-21 (2010)
Wieslaw Tryniszewski et al.
Medical science monitor : international medical journal of experimental and clinical research, 16(12), CR622-CR627 (2010-12-02)
Most of the methods don't give the comparison between blood flow at rest and after exercise. Nuclear medicine allows for such assessment and determination of muscle perfusion indexes. The aim of the study was the comparison of the radioisotopic assessment
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