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84850

Sigma-Aldrich

Sebacoyl chloride

purum, ≥95.0% (GC)

Synonyme(s) :

Sebacyl chloride

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About This Item

Formule linéaire :
ClCO(CH2)8COCl
Numéro CAS:
111-19-3
Poids moléculaire :
239.14
Numéro Beilstein :
1365665
Numéro CE :
203-843-4
Numéro MDL:
MFCD00000770
Code UNSPSC :
12162002
ID de substance PubChem :
329769323
Nomenclature NACRES :
NA.23

Qualité

purum

Niveau de qualité

200

Pureté

≥95.0% (GC)

Forme

liquid

Indice de réfraction

n20/D 1.468 (lit.)
n20/D 1.468

Point d'ébullition

168 °C/12 mmHg (lit.)

Pf

−5-−3 °C (lit.)

Densité

1.119 g/mL at 20 °C
1.121 g/mL at 25 °C (lit.)

Chaîne SMILES 

ClC(=O)CCCCCCCCC(Cl)=O

InChI

1S/C10H16Cl2O2/c11-9(13)7-5-3-1-2-4-6-8-10(12)14/h1-8H2

Clé InChI

WMPOZLHMGVKUEJ-UHFFFAOYSA-N

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Description générale

Sebacoyl chloride is a light yellow, pungent odored di-acryl chloride. It is soluble in hydrocarbons and ethers.It hydrolyzes in water, releasing hydrogen chloride.

Application

Sebacoyl chloride may be used along with hexamethylenediamine, during Schotten -Baumann reactions, to produce a polyamide (eg.Nylon 6,10).

Pictogrammes

CorrosionExclamation mark
GHS05,GHS07

Mention d'avertissement

Danger

Mentions de danger

H302,H314,H335

Classification des risques

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

235.4 °F - closed cup

Point d'éclair (°C)

113 °C - closed cup

Équipement de protection individuelle

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Certificats d'analyse (COA)

Lot/Batch Number
BCCK6743
BCCC0235
BCBS6733V
BCBS9798V
BCBH6094V

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Zhe Gong et al.
ACS biomaterials science & engineering, 6(11), 6331-6343 (2021-01-16)
Despite decades of research, spinal cord injury (SCI) still causes irreparable damage to the human body. Key challenges that hinder the regeneration and extension of neurons following SCI must be overcome, including the overexpressed glial scar formation and strong inflammatory
Zhenhua Xu et al.
International journal of pharmaceutics, 426(1-2), 182-192 (2012-01-24)
In this study we describe a novel polymer, mPPS-FA, synthesized as a potential gene transfer vector. To complete mPPS-FA, folic acid was conjugated to a backbone (named mPPS) consisting of a copolymer of methyl PEG-2000, PEI-600, and sebacoyl chloride. (1)H
Marianna Sikorska et al.
BioFactors (Oxford, England), 18(1-4), 173-183 (2003-12-30)
We have derivatised alpha-tocopherol (vitamin E) to a water-soluble polyoxyethanyl-alpha - tocopheryl sebacate (PTS) and discovered that it formed a non-covalent complex with CoQ10 at a molar ratio of 2:1 (PTS-CoQ10). This complex was water-soluble and remained stable for extended
I Montasser et al.
International journal of pharmaceutics, 335(1-2), 176-179 (2006-12-19)
Formulation of nanocapsules based on polyureas and polyamides have been tested using a patented process. This method based on polycondensation reaction of two complementary monomers and spontaneous formation of oil in water emulsion, is an alternative concept to the known
P L Madan et al.
Pharmaceutical research, 6(8), 714-718 (1989-08-01)
The effect of selected variables on the release characteristics of theophylline microcapsules prepared with 1,6-hexamethylene diamine and sebacoyl chloride via interfacial polycondensation has been investigated. The nature of the microcapsules and the release characteristics of theophylline from the microcapsules were
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