77253

Heptafluorobutyric anhydride

for GC derivatization, LiChropur^™, ≥99.0%

• Synonyme(s) : HFBA
• Formule linéaire : (CF₃CF₂CF₂CO)₂O
• Numéro CAS: 336-59-4
• Poids moléculaire : 410.06
• Beilstein: 856036
• Numéro CE : 206-410-8
• Numéro MDL: MFCD00000432
• Code UNSPSC : 12000000
• ID de substance PubChem : 329767572
• Nomenclature NACRES : NA.22

Propriétés

• Qualité: derivatization grade ((GC derivatization)); for GC derivatization; LiChropur^™
• Niveau de qualité: 100
• Essai: ≥99.0% (GC); ≥99.0%
• Forme: liquid
• Pertinence de la réaction: reagent type: derivatization reagent; reaction type: Acylations
• Technique(s): gas chromatography (GC): suitable
• Indice de réfraction: n20/D 1.287 (lit.)
• pb: 108-110 °C (lit.)
• Pf: −43 °C (lit.)
• Densité: 1.674 g/mL at 20 °C (lit.); 1.674 g/mL at 20 °C
• Chaîne SMILES: FC(F)(F)C(F)(F)C(F)(F)C(=O)OC(=O)C(F)(F)C(F)(F)C(F)(F)F
• InChI: 1S/C8F14O3/c9-3(10,5(13,14)7(17,18)19)1(23)25-2(24)4(11,12)6(15,16)8(20,21)22
• Clé InChI: UFFSXJKVKBQEHC-UHFFFAOYSA-N

Description

Description générale

Heptafluorobutyric anhydride is a perfluoroacylated acylation reagent, that forms stable, volatile derivatives with alcohols, amines, and phenols. It is majorly used to prepare electron-capturing derivatives for GC/electron capture detection. It is generally used with an acid scavenger, to help drive the reaction to completion and to prevent column damage from acidic by-products of the derivatization reaction. It is also used for the frequent testing of drugs of abuse such as, amphetamines and phencyclidine by GC-MS technique.

Application

Learn more in the Product Information

Conditionnement

Clear borosilicate glass, high hydrolytic resistance (Type I)

Remarque sur l'analyse

Suitable for derivatization of aldosterone, digoxin, digitoxin and metabolites, estradiol, postaglandins F_1α and F_2α, 3-oxo-Δ⁴-steroids, steroids and testosterone.

Autres remarques

HFAA acylates amines, amino acids and other compounds. HFBA derivatives are highly volatile: used in GC separation[1][2]

Reagent for 3-enol heptafluorobutyrate, heptafluorobutyrate, heptafluorobutyryl, 17-heptafluorobutyryl and 17-heptafluorobutyrate.

Informations légales

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H314
• Conseils de prudence: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Classification des risques: Skin Corr. 1B
• Code de la classe de stockage: 8A - Combustible corrosive hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter