68923

Esculetin

analytical standard

• Synonyme(s) : 6,7-Dihydroxycoumarin, Cichorigenin, Esculetin
• Formule empirique (notation de Hill): C₉H₆O₄
• Numéro CAS: 305-01-1
• Poids moléculaire : 178.14
• Numéro Beilstein : 152788
• Numéro CE : 206-161-5
• Numéro MDL: MFCD00006874
• Code UNSPSC : 12352200
• ID de substance PubChem : 329761226
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: analytical standard
• Niveau de qualité: 100
• Pureté: ≥97.5% (HPLC); 97.5-102.5% (NT)
• Durée de conservation: limited shelf life, expiry date on the label
• Pf: 271-273 °C (lit.)
• Format: neat
• Chaîne SMILES: Oc1cc2OC(=O)C=Cc2cc1O
• InChI: 1S/C9H6O4/c10-6-3-5-1-2-9(12)13-8(5)4-7(6)11/h1-4,10-11H
• Clé InChI: ILEDWLMCKZNDJK-UHFFFAOYSA-N

Description

Description générale

Esculetin is a derivative of coumarin, found in various plant species including Cichorium intybus (chicory), Bougainvillea spectabilis, Artemisia capillaris, etc and leaves of Citrus limonia (Rutaceae), Ceratostigma willmottianum, etc. It exhibits multiple pharmacological activities and is found to be a potent inhibitor of cyclooxygenase, 5-lipoxygenase, 12-lipoxygenase, catechol-O-methyl transferase, NADPH oxidase and xanthine oxidase enzymes.

Application

Esculetin may be used as an analytical reference standard for the determination of the analyte in biological and water samples by chromatography-based techniques. It may also be used as a standard in the quantification of the analyte in traditional herbal medicines by solid-phase extraction and micellar electrokinetic capillary methods, respectively.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable