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52517

Supelco

1,1,1,3,3,3-Hexafluoro-2-propanol

for GC derivatization, LiChropur, ≥99.8%

Synonyme(s) :

HFP, Hexafluoroisopropanol

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10 ML
250,00 €
10 X 1 ML
268,00 €
50 ML
975,00 €

250,00 €


Disponible pour expédition le08 avril 2025Détails


Devis pour commande en gros

Sélectionner une taille de conditionnement

Changer de vue
10 ML
250,00 €
10 X 1 ML
268,00 €
50 ML
975,00 €

About This Item

Formule linéaire :
(CF3)2CHOH
Numéro CAS:
Poids moléculaire :
168.04
Beilstein:
1841007
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352104
ID de substance PubChem :
Nomenclature NACRES :
NA.05

250,00 €


Disponible pour expédition le08 avril 2025Détails


Devis pour commande en gros

Qualité

derivatization grade ((GC derivatization))
for GC derivatization
LiChropur

Niveau de qualité

Essai

≥99.8% (GC)
≥99.8%

Pertinence de la réaction

reagent type: derivatization reagent
reaction type: Acylations

reagent type: derivatization reagent
reaction type: Esterifications

Technique(s)

gas chromatography (GC): suitable

Indice de réfraction

n20/D 1.275 (lit.)

pb

59 °C (lit.)

Pf

−4 °C (lit.)

Densité

1.596 g/mL at 25 °C (lit.)

Chaîne SMILES 

OC(C(F)(F)F)C(F)(F)F

InChI

1S/C3H2F6O/c4-2(5,6)1(10)3(7,8)9/h1,10H

Clé InChI

BYEAHWXPCBROCE-UHFFFAOYSA-N

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Description générale

Hexafluoroisopropanol (HFP) is generally used to denature the native state of proteins, and it also stabilizes the a-helical conformation in unfolded peptides and proteins like ß-lactoglobulin and melittin.[1]

Application

Suitable for the derivatization of glutamic acid, homovanillic, iso-homovanillic and dihydroxyphenyl acetic acids and Υ-aminobutyric acid.

Autres remarques

Reagent for hexafluoroisopropyl ester, N-pentafluoropropionyl, and trifluoroacetyl..
Size-exclusion chromatography in 1,1,1,3,3,3-hexafluoro-2-propanol[2]

Informations légales

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

Health hazardCorrosion

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Eye Dam. 1 - Repr. 2 - Skin Corr. 1A - STOT RE 2

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

No data available

Point d'éclair (°C)

No data available

Équipement de protection individuelle

Faceshields, Gloves, Goggles


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Certificats d'analyse (COA)

Lot/Batch Number

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Jie Zhu et al.
Journal of enzyme inhibition and medicinal chemistry, 33(1), 496-506 (2018-02-07)
The cholinergic hypothesis has long been a "polar star" in drug discovery for Alzheimer's disease (AD), resulting in many small molecules and biological drug candidates. Most of the drugs marketed for AD are cholinergic. Herein, we report our efforts in
Sriya Das et al.
ACS applied materials & interfaces, 3(6), 1844-1851 (2011-05-05)
We demonstrate a novel in situ polymerization technique to develop localized polymer coatings on the surface of dispersed pristine graphene sheets. Graphene sheets show great promise as strong, conductive fillers in polymer nanocomposites; however, difficulties in dispersion quality and interfacial
Cooperative a-helix formation of ?-lactoglobulin and melittin induced by hexafluoroisopropanol
Hirota, Nami, Yuji Goto, and Kazuko Mizuno.
Protein Science, 6 (2), 416-421 (1997)
Thomas H Mourey et al.
Journal of chromatography. A, 964(1-2), 169-178 (2002-08-30)
1,1,1,3,3,3-Hexafluoroisopropanol is re-examined as an eluent for size-exclusion chromatography (SEC) of polyesters, nylons, and other polar polymers. It is shown that anomalous SEC behavior reported in previous literature can be eliminated by adding 0.01 M tetraethylammonium nitrate to the eluent.
Alexis Fenyi et al.
Scientific reports, 8(1), 10788-10788 (2018-07-19)
α-synuclein fibrillar polymorphs, Tau and Aß 1-42 fibrillar assemblies have been shown to propagate, amplify and trigger the formation of protein deposits reminiscent of those present within the central nervous system of patients developing synucleinopathies, tauopathies and amyloid plaques after

Questions

1–2 sur 2 questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 réponse
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 réponse
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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